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170315s2017 xxu| s |||| 0|eng d |
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|a 9781493968633
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| 024 |
7 |
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|a 10.1007/978-1-4939-6863-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Matrix Metalloproteases :
|b Methods and Protocols /
|c edited by Charles A. Galea.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2017.
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| 300 |
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|a XI, 314 p. 56 illus., 34 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1579
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| 505 |
0 |
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|a Expression and Purification of Matrix Metalloproteinases in Escherichia coli -- Expression and Purification of a Matrix Metalloprotease Transmembrane Domain in Escherichia coli -- Heterologous Expression of the Astacin Protease Meprin b in Pichia pastoris -- Structural Studies of Matrix Metalloproteinase by X-Ray Diffraction -- Mapping Lipid Bilayer Recognition Sites of Metalloproteinases and other Prospective Peripheral Membrane Proteins -- Using Small Angle X-ray Scattering (SAXS) to Characterise the Solution Conformation and Flexibility of Matrix Metalloproteinases (MMPs) -- Molecular Dynamics Studies of Matrix Metalloproteases -- Determining the Substrate Specificity of Matrix Metalloproteases using Fluorogenic Peptide Substrates -- Time-resolved Analysis of Matrix Metalloproteinase Substrates in Complex Samples -- Identification of Protease Cleavage Sites by Charge-Based Enrichment of Protein N-termini -- Mapping the Substrate Recognition Landscapes of Metalloproteases using Comprehensive Mutagenesis -- Detection of Matrix Metalloproteinases by Zymography -- Imaging Matrix Metalloproteases in Spontaneous Colon Tumors: Validation by Correlation with Histopathology -- Virtual High-throughput Screening for Matrix Metalloproteinase Inhibitors -- Computational Approaches to Matrix Metalloprotease Drug Design -- A Simple, Adaptable Blood-Brain Barrier Cell Model for Screening Matrix Metalloproteinase Inhibitor Functionality -- Matrix Metalloproteases as Biomarkers of Disease. .
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| 650 |
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|a Biochemistry.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Galea, Charles A.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-1-4939-6863-3
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