Kinase Screening and Profiling : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Zegzouti, Hicham. (Editor ), Goueli, Said A. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:1st ed. 2016.
Colección:Methods in Molecular Biology, 1360
Materias:
LEADER 02507nam a22002895i 4500
001 000285994
005 20210826133122.0
007 cr nn 008mamaa
008 151026s2016 xxu| s |||| 0|eng d
020 |a 9781493930739 
024 7 |a 10.1007/978-1-4939-3073-9  |2 doi 
040 |a Sistema de Bibliotecas del Tecnológico de Costa Rica 
245 1 0 |a Kinase Screening and Profiling :  |b Methods and Protocols /  |c edited by Hicham Zegzouti, Said A. Goueli. 
250 |a 1st ed. 2016. 
260 # # |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2016. 
300 |a X, 223 p. 45 illus., 26 illus. in color. :  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in Molecular Biology,  |v 1360 
505 0 |a HTRF Kinase Assay Development and Methods in Inhibitor Characterization.- Application of Eukaryotic Elongation Factor-2 Kinase (eEF-2K) for Cancer Therapy: Expression, Purification, and High-Throughput Inhibitor Screening.- Recombinant Kinase Production and Fragment Screening by NMR Spectroscopy -- Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Format Applied to Yes1 Tyrosine Kinase, Glucokinase and PI5P4Kα Lipid Kinase.- Using Bioluminescent Kinase Profiling Strips to Identify Kinase Inhibitor Selectivity and Promiscuity.- Measuring Activity of Phosphoinositide Lipid Kinases Using a Bioluminescent ADP-Detecting Assay.- A High-Throughput Radiometric Kinase Assay -- A High Content Assay to Screen for Modulators of EGFR Function.- Monitoring Protein Kinase Expression and Phosphorylation in Cell Lysates with Antibody Microarrays -- From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38 MAPK Inhibitors -- Genetically Encoded Fluorescent Indicators to Visualize Protein Phosphorylation in Living Cells.- Characterization of an Engineered Src Kinase to Study Src Signaling and Biology -- Screening One-Bead-One-Compound Peptide Libraries for Optimal Kinase Substrates -- Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays -- Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries. 
650 0 |a Proteins . 
650 1 4 |a Protein Science. 
700 1 |a Zegzouti, Hicham.  |e editor. 
700 1 |a Goueli, Said A.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks