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03146nam a22003615i 4500 |
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20210517093537.0 |
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cr nn 008mamaa |
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100715s2010 xxu| s |||| 0|eng d |
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|a 9781607610588
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| 024 |
7 |
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|a 10.1007/978-1-60761-058-8
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Mouse Models for Drug Discovery :
|b Methods and Protocols /
|c edited by Gabriele Proetzel, Michael V. Wiles.
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| 250 |
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|a 1st ed. 2010.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2010.
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| 300 |
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|a XII, 421 p. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 602
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| 505 |
0 |
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|a Improving Toxicity Screening and Drug Development by Using Genetically Defined Strains -- The Sophisticated Mouse: Protecting a Precious Reagent -- Genetically Engineered Mouse Models in Drug Discovery Research -- Engineering the Mouse Genome to Model Human Disease for Drug Discovery -- Profiling of Drug Action Using Reporter Mice and Molecular Imaging -- Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies -- Development of Novel Major Histocompatibility Complex Class I and Class II-Deficient NOD-SCID IL2R Gamma Chain Knockout Mice for Modeling Human Xenogeneic Graft-Versus-Host Disease -- Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans -- Mouse Models of Type II Diabetes Mellitus in Drug Discovery -- Cholesterol Absorption and Metabolism -- Collagen-Induced Arthritis in Mice -- Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening -- Models of Metastasis in Drug Discovery -- Methods for Evaluating Effects of an Irinotecan + 5-Fluorouracil/Leucovorin (IFL) Regimen in an Orthotopic Metastatic Colorectal Cancer Model Utilizing In Vivo Bioluminescence Imaging -- CML Mouse Model in Translational Research -- Mouse Models for Studying Depression-Like States and Antidepressant Drugs -- Virus-Delivered RNA Interference in Mouse Brain to Study Addiction-Related Behaviors -- Experimental Models of Anxiety for Drug Discovery and Brain Research -- Mouse Models of Neurodegenerative Diseases: Criteria and General Methodology -- Neuromuscular Disease Models and Analysis -- Murine Model of Cutaneous Infection with Streptococcus pyogenes -- Murine Model of Pneumococcal Pneumonia -- Murine Model of Polymicrobial Septic Peritonitis Using Cecal Ligation and Puncture (CLP) -- Erratum to: Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Laboratory medicine.
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| 650 |
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0 |
|a Zoology.
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| 650 |
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0 |
|a Animal models in research.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Laboratory Medicine.
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| 650 |
2 |
4 |
|a Zoology.
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| 650 |
2 |
4 |
|a Animal Models.
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| 700 |
1 |
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|a Proetzel, Gabriele.
|e editor.
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| 700 |
1 |
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|a Wiles, Michael V.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|