Mouse Models for Drug Discovery : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Proetzel, Gabriele. (Editor ), Wiles, Michael V. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2010.
Edición:1st ed. 2010.
Colección:Methods in Molecular Biology, 602
Materias:
Tabla de Contenidos:
  • Improving Toxicity Screening and Drug Development by Using Genetically Defined Strains
  • The Sophisticated Mouse: Protecting a Precious Reagent
  • Genetically Engineered Mouse Models in Drug Discovery Research
  • Engineering the Mouse Genome to Model Human Disease for Drug Discovery
  • Profiling of Drug Action Using Reporter Mice and Molecular Imaging
  • Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies
  • Development of Novel Major Histocompatibility Complex Class I and Class II-Deficient NOD-SCID IL2R Gamma Chain Knockout Mice for Modeling Human Xenogeneic Graft-Versus-Host Disease
  • Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans
  • Mouse Models of Type II Diabetes Mellitus in Drug Discovery
  • Cholesterol Absorption and Metabolism
  • Collagen-Induced Arthritis in Mice
  • Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening
  • Models of Metastasis in Drug Discovery
  • Methods for Evaluating Effects of an Irinotecan + 5-Fluorouracil/Leucovorin (IFL) Regimen in an Orthotopic Metastatic Colorectal Cancer Model Utilizing In Vivo Bioluminescence Imaging
  • CML Mouse Model in Translational Research
  • Mouse Models for Studying Depression-Like States and Antidepressant Drugs
  • Virus-Delivered RNA Interference in Mouse Brain to Study Addiction-Related Behaviors
  • Experimental Models of Anxiety for Drug Discovery and Brain Research
  • Mouse Models of Neurodegenerative Diseases: Criteria and General Methodology
  • Neuromuscular Disease Models and Analysis
  • Murine Model of Cutaneous Infection with Streptococcus pyogenes
  • Murine Model of Pneumococcal Pneumonia
  • Murine Model of Polymicrobial Septic Peritonitis Using Cecal Ligation and Puncture (CLP)
  • Erratum to: Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.