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100715s2010 xxu| s |||| 0|eng d |
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|a 9781607614012
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| 024 |
7 |
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|a 10.1007/978-1-60761-401-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Immunotoxicity Testing :
|b Methods and Protocols /
|c edited by Rodney R. Dietert.
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| 250 |
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|a 1st ed. 2010.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2010.
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| 300 |
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|a X, 430 p. 43 illus. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 598
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| 505 |
0 |
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|a Immunotoxicology Testing: Past and Future -- Overview and Health-Risk Considerations -- Developmental Immunotoxicity (DIT): The Why, When, and How of DIT Testing -- An In Vivo Tiered Approach to Test Immunosensitization by Low Molecular Weight Compounds -- Risk of Autoimmune Disease: Challenges for Immunotoxicity Testing -- Markers of Inflammation -- Evaluating Macrophages in Immunotoxicity Testing -- Immunotoxicity and Host Resistance Models -- Host Resistance Assays Including Bacterial Challenge Models -- Viral Host Resistance Studies -- Parasite Challenge as Host Resistance Models for Immunotoxicity Testing -- Tumor Challenges in Immunotoxicity Testing -- Testing Protocols in Rodents and Other Laboratory Animals -- The T-Dependent Antibody Response to Keyhole Limpet Hemocyanin in Rodents -- The Sheep Erythrocyte T-Dependent Antibody Response (TDAR) -- The Delayed Type Hypersensitivity Assay Using Protein and Xenogeneic Cell Antigens -- The Cytotoxic T Lymphocyte Assay for Evaluating Cell-Mediated Immune Function -- NK Cell Assays in Immunotoxicity Testing -- The Local Lymph Node Assay and Skin Sensitization Testing -- Use of Contact Hypersensitivity in Immunotoxicity Testing -- Evaluation of Apoptosis in Immunotoxicity Testing -- Dendritic Cells in Immunotoxicity Testing -- Evaluating Cytokines in Immunotoxicity Testing -- Flow Cytometry in Preclinical Drug Development -- Enhanced Histopathology Evaluation of Lymphoid Organs -- Immunotoxicity Testing in Nonhuman Primates -- Evaluation in Humans -- Fundamentals of Clinical Immunotoxicology -- Wildlife Testing -- In Vivo Functional Tests for Assessing Immunotoxicity in Birds -- In Vitro Alternatives -- In Vitro Testing for Direct Immunotoxicity: State of the Art.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Laboratory medicine.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Science, Humanities and Social Sciences, multidisciplinary.
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| 650 |
2 |
4 |
|a Laboratory Medicine.
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| 700 |
1 |
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|a Dietert, Rodney R.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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