Immunotoxicity Testing : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dietert, Rodney R. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2010.
Edición:1st ed. 2010.
Colección:Methods in Molecular Biology, 598
Materias:
Tabla de Contenidos:
  • Immunotoxicology Testing: Past and Future
  • Overview and Health-Risk Considerations
  • Developmental Immunotoxicity (DIT): The Why, When, and How of DIT Testing
  • An In Vivo Tiered Approach to Test Immunosensitization by Low Molecular Weight Compounds
  • Risk of Autoimmune Disease: Challenges for Immunotoxicity Testing
  • Markers of Inflammation
  • Evaluating Macrophages in Immunotoxicity Testing
  • Immunotoxicity and Host Resistance Models
  • Host Resistance Assays Including Bacterial Challenge Models
  • Viral Host Resistance Studies
  • Parasite Challenge as Host Resistance Models for Immunotoxicity Testing
  • Tumor Challenges in Immunotoxicity Testing
  • Testing Protocols in Rodents and Other Laboratory Animals
  • The T-Dependent Antibody Response to Keyhole Limpet Hemocyanin in Rodents
  • The Sheep Erythrocyte T-Dependent Antibody Response (TDAR)
  • The Delayed Type Hypersensitivity Assay Using Protein and Xenogeneic Cell Antigens
  • The Cytotoxic T Lymphocyte Assay for Evaluating Cell-Mediated Immune Function
  • NK Cell Assays in Immunotoxicity Testing
  • The Local Lymph Node Assay and Skin Sensitization Testing
  • Use of Contact Hypersensitivity in Immunotoxicity Testing
  • Evaluation of Apoptosis in Immunotoxicity Testing
  • Dendritic Cells in Immunotoxicity Testing
  • Evaluating Cytokines in Immunotoxicity Testing
  • Flow Cytometry in Preclinical Drug Development
  • Enhanced Histopathology Evaluation of Lymphoid Organs
  • Immunotoxicity Testing in Nonhuman Primates
  • Evaluation in Humans
  • Fundamentals of Clinical Immunotoxicology
  • Wildlife Testing
  • In Vivo Functional Tests for Assessing Immunotoxicity in Birds
  • In Vitro Alternatives
  • In Vitro Testing for Direct Immunotoxicity: State of the Art.