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110803s2011 xxu| s |||| 0|eng d |
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|a 9781617791703
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| 024 |
7 |
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|a 10.1007/978-1-61779-170-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a In Vitro Neurotoxicology :
|b Methods and Protocols /
|c edited by Lucio G. Costa, Gennaro Giordano, Marina Guizzetti.
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| 250 |
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|a 1st ed. 2011.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2011.
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| 300 |
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|a XII, 415 p. 66 illus. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 758
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| 505 |
0 |
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|a In Vitro Neurotoxicology: An Introduction -- Primary Neurons in Culture and Neuronal Cell Lines for In Vitro Neurotoxicological Studies -- Determination of Metal Interactions with the Chaperone Hspa5 in Human Astrocytoma Cells and Rat Astrocyte Primary Cultures -- Microglia Cell Culture: A Primer for the Novice -- Neural Stem Cells for Developmental Neurotoxicity Studies -- Preparation, Maintenance, and Use of Serum-Free Aggregating Brain Cell Cultures -- Neurospheres as a Model for Developmental Neurotoxicity Testing -- Acute Hippocampal Slice Preparation and Hippocampal Slice Cultures -- Glia-Neuron Sandwich Co-Cultures: An In Vitro Approach to Evaluate Cell-to-Cell Communication in Neuroinflammation and Neurotoxicity -- In Vitro Models to Study the Blood Brain Barrier -- Measurements of Cell Death in Neuronal and Glial Cells -- Measurements of Neuronal Apoptosis -- Measurement of Isoprostanes as Markers of Oxidative Stress -- Assessment of Glutathione Homeostasis -- Assessing Neuronal Bioenergetic Status -- Fluorescent Assessment of Intracellular Calcium in Individual Cells -- Homeostatic Regulation of Glutamate Neurotransmission in Primary Neuronal Cultures -- Detection of Nitric Oxide Formation in Primary Neural Cells and Tissues -- JNK3-Mediated Apoptotic Cell Death in Primary Dopaminergic Neurons -- Measurement of Proteasomal Dysfunction in Cell Models of Dopaminergic Degeneration -- Cell Signaling and Neurotoxicity: Protein Kinase C In Vitro and In Vivo -- Cell Signaling and Neurotoxicity: 3H-Arachidonic Acid Release (Phospholipase A2) in Cerebellar Granule Neurons -- Quantitative Assessment of Neurite Outgrowth in PC12 Cells -- Measurements of Astrocyte Proliferation -- Quantification of Synaptic Structure Formation in Co-Cultures of Astrocytes and Hippocampal Neurons -- Volume Measurements in Cultured Primary Astrocytes -- Assessment of Cholesterol Homeostasis in Astrocytes and Neurons -- Dose-Response or Dose-Effect Curves in In Vitro Experiments and Their Use to Study Combined Effects of Neurotoxicants.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Neurobiology.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Neurobiology.
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| 700 |
1 |
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|a Costa, Lucio G.
|e editor.
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| 700 |
1 |
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|a Giordano, Gennaro.
|e editor.
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| 700 |
1 |
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|a Guizzetti, Marina.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|