Ligand-Macromolecular Interactions in Drug Discovery : Methods and Protocols /
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2010.
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| Edición: | 1st ed. 2010. |
| Colección: | Methods in Molecular Biology,
572 |
| Materias: |
Tabla de Contenidos:
- Reviews
- An Historical Overview of Drug Discovery
- Ligand Macromolecule Interactions: Theoretical Principles of Molecular Recognition
- X-Ray Crystallography in Drug Discovery
- Virtual Screening of Compound Libraries
- Protocols
- Combinatorial Chemistry and the Synthesis of Compound Libraries
- Ligand-Based Nuclear Magnetic Resonance Screening Techniques
- Isothermal Titration Calorimetry and Differential Scanning Calorimetry
- Adaptive Combinatorial Design of Focused Compound Libraries
- Chemical Microarrays: A New Tool for Discovery Enzyme Inhibitors
- Fluorescence Polarization and Time-Resolved Fluorescence Resonance Energy Transfer Techniques for PI3K Assays
- Small Molecule Protein Interaction Profiling with Functional Protein Microarrays
- Capillary Electrophoresis in Drug Discovery
- SPR in Drug Discovery: Searching Bioactive Compounds in Plant Extracts
- Application of Frontal Affinity Chromatography with Mass Spectrometry (FAC#x2013;MS) for Stereospecific Ligand#x2013;Macromolecule Interaction, Detection and Screening
- GPC Spin Column HPLC#x2013;ESI-MS Methods for Screening Drugs Noncovalently Bound to Proteins
- A Scintillation Proximity Assay for Fatty Acid Amide Hydrolase Compatible with Inhibitor Screening
- A Natural Products Approach to Drug Discovery: Probing Modes of Action of Antitumor Agents by Genome-Scale cDNA Library Screening
- Ligand#x2013;Macromolecule Interactions in Live Cells by Fluorescence Correlation Spectroscopy.