Programmed Necrosis : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Ting, Adrian T. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Humana, 2018.
Edición:1st ed. 2018.
Colección:Methods in Molecular Biology, 1857
Materias:
Tabla de Contenidos:
  • Tools in the Art of Studying Necroptosis
  • Loss-of-Function RNAi Screen to Identify Necrosis-Signaling Molecules
  • Chemical Library Screens to Identify Pharmacological Modulators of Necroptosis
  • Distinguishing Necroptosis from Apoptosis
  • Methods for Studying TNF-Mediated Necroptosis in Cultured Cells
  • Analysis of Necroptosis in Bone Marrow-Derived Macrophages
  • Generation and Use of Chimeric RIP Kinase Molecules to Study Necroptosis
  • Detection of MLKL Oligomerization during Programmed Necrosis
  • Analysis of Cytokine- and Influenza A Virus-Driven RIPK3 Necrosome Formation
  • Detection of RIPK1 in the FADD-Containing Death Inducing Signaling Complex (DISC) during Necroptosis
  • Use of RIP1 Kinase Small Molecule Inhibitors in Studying Necroptosis
  • Analyzing Necroptosis using a RIPK1 Kinase Inactive Mouse Model of TNF Shock
  • Assessment of In Vivo Kidney Cell Death: Acute Kidney Injury
  • Assessment of In Vivo Kidney Cell Death: Glomerular Injury
  • Detection of Necroptosis by Phospho-RIPK3 Immunohistochemical Labeling
  • Characterization of the TNFR1-SC using 'Modified Tandem Affinity Purification' in Conjunction with Liquid Chromatography-Mass Spectrometry (LC-MS)
  • Monitoring RIPK1 Phosphorylation in the TNFR1 Signaling Complex
  • Analysis of CYLD Proteolysis by Caspase-8 in Bone Marrow-Derived Macrophages.