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181211s2019 xxu| s |||| 0|eng d |
| 020 |
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|a 9781493989942
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| 024 |
7 |
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|a 10.1007/978-1-4939-8994-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Pre-Clinical Models :
|b Techniques and Protocols /
|c edited by Paul C. Guest.
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| 250 |
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|a 1st ed. 2019.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2019.
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| 300 |
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|a XIII, 343 p. 90 illus., 73 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1916
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| 505 |
0 |
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|a A Guide to Mass Spectrometry-based Quantitative Proteomics -- Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- Monosodium Glutamate (MSG)-induced Animal Model of Type 2 Diabetes -- The Elevated Plus Maze Test for Measuring Anxiety-like Behaviour in Rodents -- The Forced Swim Test for Depression-like Behaviour in Rodents -- Object Burying Test for Assessment of Obsessive Compulsive Behaviours in Mice -- The Nest Building Test in Mice for Assessment of General Well-being -- Mouse Free Dyadic Social Interaction Test -- The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behaviour -- The Y-maze for Assessment of Spatial Working and Reference Memory in Mice -- Maturation of a Human Oligodendrocyte Cell Line -- Monitoring Age-related Changes in the Lactate/pyruvate Ratio using a Colorimetric Assay in a C. elegans Model of Increased Lifespan -- Isolation and Characterisation of Different Mesenchymal Stem Cell Populations from Rat Femur -- Characterization of an Animal Model of Autism and Social Interaction -- Assaying Reproductive Capacity in Female Rodents -- Experimental Model of Hindlimb Suspension-Induced Skeletal Muscle Atrophy in Rodents -- An Analysis of the Intracellular Signal Transduction of Peripheral Blood Leukocytes in Animal Models of Diabetes using Flow Cytometry -- Characterization of the db/db Mouse Model of Type 2 Diabetes -- Characterization of the Goto-Kakizaki (GK) Rat Model of Type 2 Diabetes -- Characterization of Human Transplantable Insulinoma Cells -- Preparation of Islets from Rat Pancreas and Assessment of Islet Function -- Cryopreservation of Red Blood Cells -- Molecular Characterization of Human Leukemia 60 (HL-60) Cells as a Model of Acute Myelogenous Leukemia Post Cryo-preservation -- Reprogramming of Human Melanocytes and Melanoma cells with Yamanaka Factors -- The Use of 3T3-L1 Murine Preadipocytes as a Model of Adipogenesis -- Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study its Metabolic Role in Cancer Research -- The use of Primary Hepatocytes in Assessment of Drug Safety and Toxicity -- OVA-induced Allergic Airway Inflammation Mouse Model -- Description of Ovariectomy Protocol in Mice -- A Rat Eye Lens Model of Cataract Formation -- A Complete Proteomic Workflow to Study Brain-Related Disorders via Postmortem Tissue -- Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 β-Cell Line- a Preclinical Model for Type 2 Diabetes.
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| 650 |
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|a Pharmacology.
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| 650 |
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|a Animal models in research.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 650 |
2 |
4 |
|a Animal Models.
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| 700 |
1 |
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|a Guest, Paul C.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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