RUNX Proteins in Development and Cancer /
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , , , , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Singapore :
Springer Singapore : Imprint: Springer,
2017.
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| Edición: | 1st ed. 2017. |
| Colección: | Advances in Experimental Medicine and Biology,
962 |
| Materias: |
Tabla de Contenidos:
- RUNX in invertebrates
- Structure and biophysics of CBFb/RUNX and its transcription products
- Covalent modification of RUNX proteins: structure affects function
- The role of Runx1 in embryonic blood cell formation
- RUNX1 structure and function in blood cell development
- Roles of Runx2 in skeletal development
- Roles of Runx genes in nervous system development
- Runx family genes in tissue stem cell dynamics
- Roles of RUNX1 enhancer in normal hematopoiesis and leukemogenesis
- RUNX1-ETO leukemia
- Clinical relevance of RUNX1 and CBFB alterations in acute myeloid leukemia and other hematological disorders
- Mechanism of ETV6-RUNX1 leukemia
- ETV6-RUNX1+ acute lymphoblastic leukemia in identical twins
- Molecular basis and targeted inhibition of CBFb-SMMHC acute myeloid leukemia
- The RUNX genes as conditional oncogenes: insights from retroviral targeting and mouse models
- RUNX1 and CBFb mutations and activities of their wild-type alleles in AML
- Roles of RUNX in B cell immortalization
- Roles of RUNX in solid tumors
- RUNX3 and p53: How two tumor suppressors cooperate against oncogenic Ras
- Runx3 and cell fate decisions in pancreas cancer
- RUNX genes in breast cancer and the mammary lineage
- Runx3 in immunity, inflammation and cancer
- Roles of RUNX complexes in immune cell development
- CBFb and HIV infection
- Roles of RUNX in Hippo pathway signaling
- Roles of RUNX in hypoxia-induced responses and angiogenesis
- The emerging roles of RUNX transcription factors in Epithelial-Mesenchymal Transition
- Regulatory role of RUNX1 and RUNX3 in the maintenance of genomic integrity.