Proteomics for Drug Discovery : Methods and Protocols /
| Autor Corporativo: | |
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| Otros Autores: | , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2017.
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| Edición: | 1st ed. 2017. |
| Colección: | Methods in Molecular Biology,
1647 |
| Materias: |
Tabla de Contenidos:
- A Photoaffinity Labeling-Based Chemoproteomics Strategy for Unbiased Target Deconvolution of Small Molecule Drug Candidates
- Multiplexed Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry Quantification of Cancer Signaling Proteins
- Monitoring Dynamic Changes of the Cell Surface Glycoproteome by Quantitative Proteomics
- High Resolution Parallel Reaction Monitoring with Electron Transfer Dissociation for Middle-Down Proteomics: An Application to Study the Quantitative Changes Induced by Histone Modifying Enzyme Inhibitors and Activators
- Preparation and Immunoaffinity Depletion of Fresh Frozen Tissue Homogenates for Mass Spectrometry-Based Proteomics in the Context of Drug Target/Biomarker Discovery
- Target Identification Using Cell Permeable and Cleavable Chloroalkane Derivatized Small Molecules
- Microfluidics-Mass Spectrometry of Protein-Carbohydrate Interactions: Applications to Development of Therapeutics and Biomarker Discovery
- Studying Protein-Protein Interactions by Biotin AP-Tagged Pulldown and LTQ-Orbitrap Mass Spectrometry
- Post-Translational Modification Profiling-Functional Proteomics for the Analysis of Immune Regulation
- Reverse Phase Protein Arrays and Drug Discovery
- Probing Protein Kinase-ATP Interactions Using a Fluorescent ATP Analog
- Preparation of Disease-Related Protein Assemblies for Single Particle Electron Microscopy
- Identification of Lipid-Binding Modulators Using the Protein-Lipid Overlay Assay
- Resazurin Live Cell Assay: Setup and Fine-Tuning for Reliable Cytotoxicity
- Exploring Protein-Protein Interactions as Drug Targets for Anti-Cancer Therapy with In Silico Workflows
- Method to Identify Silent Codon Mutations that May Alter Peptide Elongation Kinetics and Co-Translational Protein Folding
- In Silico Design of Anticancer Peptides
- Docking and Virtual Screening in Drug Discovery
- Bioinformatics Resources for Interpreting Proteomics Mass Spectrometry Data.