Organic Cation Transporters : Integration of Physiology, Pathology, and Pharmacology /
| Autor Corporativo: | |
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| Otros Autores: | , , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Materias: |
Tabla de Contenidos:
- Introduction to the cellular transport of organic cations
- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism
- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity
- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy
- Physiological and pathological regulation of transporters for organic cations
- Endocrine and metabolic regulation of transporters for organic cations
- Organic cation transporters (OCTs) as modulators of behavior and mood
- Organic cation transporters as modulators of neurodegeneration and neuroprotection
- Translational relevance of animal models for the study of organic cation transporter function
- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.