New Agents for the Treatment of Acute Lymphoblastic Leukemia /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Saha, Vaskar. (Editor ), Kearns, Pamela. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer New York : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Materias:
Tabla de Contenidos:
  • The need for new agents
  • Identifying pre-clinical agents
  • Pre-clinical evaluation
  • Design of early phase trials
  • Strategies for trial design and analyses
  • Overview on Molecular and Animal models of ALL
  • Apoptosis, BCL2
  • Targeting Stem Cells
  • Nucleoside Analogues
  • Flt3 Inhibitors
  • Tyrosine Kinase Inhibitors
  • Monoclonal Antibodies
  • Proteasome inhibitors
  • Targeting epigenetic pathways in ALL.- Incorporating new therapies in frontline protocols.-.