|
|
|
|
| LEADER |
02884nam a22003255i 4500 |
| 001 |
000289659 |
| 005 |
20210604085925.0 |
| 007 |
cr nn 008mamaa |
| 008 |
100812s2010 xxu| s |||| 0|eng d |
| 020 |
|
|
|a 9781607617563
|
| 024 |
7 |
|
|a 10.1007/978-1-60761-756-3
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Protein Misfolding and Cellular Stress in Disease and Aging :
|b Concepts and Protocols /
|c edited by Peter Bross, Niels Gregersen.
|
| 250 |
|
|
|a 1st ed. 2010.
|
| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2010.
|
| 300 |
|
|
|a XI, 330 p. 54 illus., 4 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Methods in Molecular Biology,
|v 648
|
| 505 |
0 |
|
|a Concepts -- Protein Misfolding and Cellular Stress: An Overview -- Protein Aggregation Diseases: Toxicity of Soluble Prefibrillar Aggregates and Their Clinical Significance -- Consequences of Stress in the Secretary Pathway: The ER Stress Response and Its Role in the Metabolic Syndrome -- What Role Does Mitochondrial Stress Play in Neurodegenerative Diseases? -- Autophagy in Disease -- Mitophagy and Mitoptosis in Disease Processes -- Cellular Stress and Protein Misfolding During Aging -- Measuring Consequences of Protein Misfolding and Cellular Stress Using OMICS Techniques -- Protocols -- Production of Cells with Targeted Integration of Gene Variants of Human ABC Transporter for Stable and Regulated Expression Using the Flp Recombinase System -- Stress Response Profiles in Human Fibroblasts Exposed to Heat Shock or Oxidative Stress -- Examining Ubiquitinated Protein Aggregates in Tissue Sections -- Determination of Proteasomal Activities -- Measurement of Autophagy in Cells and Tissues -- Transcription Factor Sequestration by Polyglutamine Proteins -- Biological Membranes as Protein Aggregation Matrices and Targets of Amyloid Toxicity -- Measurement of Mitochondrial ROS Production -- In Vivo Detection of Oxidized Proteins: A Practical Approach to Tissue-Derived Mitochondria -- Measurement of Oxidized/Reduced Glutathione Ratio -- Determination of Altered Mitochondria Ultrastructure by Electron Microscopy -- Assessing Bad Sub-cellular Localization Under Conditions Associated with Prevention or Promotion of Mitochondrial Permeability Transition-Dependent Toxicity -- A Cellular Viability Assay to Monitor Drug Toxicity -- Rescue of Misfolded Proteins and Stabilization by Small Molecules.
|
| 650 |
|
0 |
|a Cell biology.
|
| 650 |
|
0 |
|a Proteomics.
|
| 650 |
1 |
4 |
|a Cell Biology.
|
| 650 |
2 |
4 |
|a Proteomics.
|
| 700 |
1 |
|
|a Bross, Peter.
|e editor.
|
| 700 |
1 |
|
|a Gregersen, Niels.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|
| 900 |
|
|
|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|