Peroxisome Proliferator-Activated Receptors : Discovery and Recent Advances /

Detalles Bibliográficos
Autores principales: Youssef, Jihan A. (Autor), Badr, Mostafa Z. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2013.
Edición:1st ed. 2013.
Materias:
Tabla de Contenidos:
  • Introduction.- History of PPAR Discovery: Peroxisomes
  • Peroxisomal biogenesis and diseases
  • Peroxisome proliferation.- Peroxisome Proliferator-Activated Receptors: Chromosomal location and gene polymorphism
  • Protein structure
  • PPAR Ligands: Endogenous ligands
  • Exogenous PPAR modulators
  • Tissue Distribution and Versatile Functions of PPARs: Neurological functions of PPARs.- PPARs and the cardiovascular system.- PPARs in pulmonary physiology and disease.- Gastrointestinal roles of PPARs.- PPAR functions in the liver.- Roles of PPARs in the pancreas.- PPARs in the urinary tract physiology and pathophysiology.- PPARs in the reproductive system
  • Bone metabolism and PPARs.- Roles of PPARs in skeletal muscle biology.- Skin PPARs.- PPARs and Drug Metabolism
  • Molecular Aspects of PPAR Actions: Posttranslational control of PPARs.- Mechanism of action.- Animal Models in PPAR Research.- Safety of PPAR Agonists.- The Future of PPAR Research.