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160401s2016 gw | s |||| 0|eng d |
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|a 9783319222790
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| 024 |
7 |
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|a 10.1007/978-3-319-22279-0
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 100 |
1 |
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|a Sinkovics, Joseph G.
|e author.
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|a RNA/DNA and Cancer /
|c by Joseph G. Sinkovics.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
# |
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a XI, 815 p. 75 illus., 52 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Preface. Introductions. I THE PRIMORDIAL RNA/DNA COMPLEX EVOLVING -- The Primordial Genes Are Conserved as Stem Cell Genes and Proto-Oncogenes -- The First Cells Ascend -- Eukaryotic Single Cells and the First Cell Communities Then and Now -- A Highly Effective Immune System Predating Adaptive Immunity -- Elements of Adaptive Immunity Self-Assemble -- The RNA/DNA Complex at Work -- YY Proteins -- Elusive Alleles -- The Long Trajectory of the IGF-like Receptor and Its Ligands -- Primordial Fused Genes Become Oncogenes and Encode Oncoproteins -- Performance in the Laboratory -- Inbuilt Errors not yet Corrected -- Errors or Inherent Attributes for the Sustenance of Unicellular Life -- Viral Genomic Insertions into the Host Cell's Genome -- Viral and Cellular Proteins Interact -- Light Cast to Broken DNA, Its Repair, and Consequences -- Undisciplined Introns -- Elementary Epigenomics -- RNA/DNA: Bioengineers Supreme -- II THE ONCOGENOME -- Seamless Unity of the Nucleus and Cytoplasm: the Membranes Are Permeable -- Endogenously Initiated Immortalization is Welcome. Enforced Carcinogenesis by Exogenous Alien Initiator Is Resisted -- A Condensed Compendium -- "Malignant Transformation" -- III THE HUMAN CEREBRAL CORTICAL DNA AGAINST CANCER CELL DNA -- Will the Human Cerebral Cortex Subdue the Oncogenome?- In Self-Defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Mobilize All Its Remaining Survival Pathways -- The Cancer Cell Viewed as a Unicellular Parasite (an Amoeba) -- Astute Observers Withstand Derision -- "Making Cancer History" at M.D. Anderson Hospital -- SUMMARY -- Appendix 1 -- Appendix 2 -- Index. .
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| 650 |
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|a Cancer research.
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| 650 |
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|a Cell biology.
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| 650 |
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|a Immunology.
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| 650 |
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|a Oncology .
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| 650 |
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4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Cell Biology.
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| 650 |
2 |
4 |
|a Immunology.
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| 650 |
2 |
4 |
|a Oncology.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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