RNA/DNA and Cancer /

Detalles Bibliográficos
Autor principal: Sinkovics, Joseph G. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Materias:
Tabla de Contenidos:
  • Preface. Introductions. I THE PRIMORDIAL RNA/DNA COMPLEX EVOLVING
  • The Primordial Genes Are Conserved as Stem Cell Genes and Proto-Oncogenes
  • The First Cells Ascend
  • Eukaryotic Single Cells and the First Cell Communities Then and Now
  • A Highly Effective Immune System Predating Adaptive Immunity
  • Elements of Adaptive Immunity Self-Assemble
  • The RNA/DNA Complex at Work
  • YY Proteins
  • Elusive Alleles
  • The Long Trajectory of the IGF-like Receptor and Its Ligands
  • Primordial Fused Genes Become Oncogenes and Encode Oncoproteins
  • Performance in the Laboratory
  • Inbuilt Errors not yet Corrected
  • Errors or Inherent Attributes for the Sustenance of Unicellular Life
  • Viral Genomic Insertions into the Host Cell’s Genome
  • Viral and Cellular Proteins Interact
  • Light Cast to Broken DNA, Its Repair, and Consequences
  • Undisciplined Introns
  • Elementary Epigenomics
  • RNA/DNA: Bioengineers Supreme
  • II THE ONCOGENOME
  • Seamless Unity of the Nucleus and Cytoplasm: the Membranes Are Permeable
  • Endogenously Initiated Immortalization is Welcome. Enforced Carcinogenesis by Exogenous Alien Initiator Is Resisted
  • A Condensed Compendium
  • “Malignant Transformation”
  • III THE HUMAN CEREBRAL CORTICAL DNA AGAINST CANCER CELL DNA
  • Will the Human Cerebral Cortex Subdue the Oncogenome?- In Self-Defense, the Cancer Cell Reactivates Its Primordial Genome Loaded with Proviruses in Order to Mobilize All Its Remaining Survival Pathways
  • The Cancer Cell Viewed as a Unicellular Parasite (an Amoeba)
  • Astute Observers Withstand Derision
  • “Making Cancer History” at M.D. Anderson Hospital
  • SUMMARY
  • Appendix 1
  • Appendix 2
  • Index. .