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03045nam a22003135i 4500 |
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000289914 |
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20210601091908.0 |
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cr nn 008mamaa |
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130703s2013 xxu| s |||| 0|eng d |
| 020 |
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|a 9781627034357
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| 024 |
7 |
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|a 10.1007/978-1-62703-435-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Pharmacogenomics :
|b Methods and Protocols /
|c edited by Federico Innocenti, Ron H.N. van Schaik.
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| 250 |
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|a 2nd ed. 2013.
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| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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| 300 |
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|a XIII, 359 p. 56 illus., 33 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1015
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| 505 |
0 |
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|a Pharmacogenomics: Historical Perspective and Current Status -- Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping -- Clinical SNP Detection by the SmartAmp Method -- MALDI-TOF Mass Spectrometry -- TaqMan® Drug Metabolism Genotyping Assays for the Detection of Human Polymorphisms Involved in Drug Metabolism -- Pyrosequencing of Clinically Relevant Polymorphisms -- Pharmacogenetics Using Luminex® xMAP® Technology: Method for Developing a Custom Multiplex Single Nucleotide Polymorphism Mutation Assay -- Use of Linkage Analysis, Genome-Wide Association Studies, and Next-Generation Sequencing in the Identification of Disease-Causing Mutations -- The GoldenGate Genotyping Assay: Custom Design, Processing, and Data Analysis -- Genome-Wide Gene Expression Profiling, Genotyping, and Copy Number Analyses of Acute Myeloid Leukemia Using Affymetrix GeneChips -- Epigenetic Techniques in Pharmacogenetics -- Plasmid Derived External Quality Controls for Genetic Testing -- Allelic Imbalance Assays to Quantify Allele-Specific Gene Expression and Transcription Factor Binding -- SCAN: A Systems Biology Approach to Pharmacogenomic Discovery -- Methods to Examine the Impact of Nonsynonymous SNPs on Protein Degradation and Function of Human ABC Transporter -- In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism -- In Vitro and In Vivo Mouse Models for Pharmacogenetic Studies -- The Hydrodynamic Tail Vein Assay as a Tool for the Study of Liver Promoters and Enhancers -- A Guide to the Current Web-Based Resources in Pharmacogenomics -- PharmGKB: The Pharmacogenomics Knowledge Base -- Genetic Databases in Pharmacogenomics: The Frequency of Inherited Disorders Database (FINDbase) -- Development of Predictive Models for Estimating Warfarin Maintenance Dose Based on Genetic and Clinical Factors -- Evidence Based Drug Dosing and Pharmacotherapeutic Recommendations Per Genotype.
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| 650 |
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0 |
|a Pharmacology.
|
| 650 |
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0 |
|a Human genetics.
|
| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
|
| 650 |
2 |
4 |
|a Human Genetics.
|
| 700 |
1 |
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|a Innocenti, Federico.
|e editor.
|
| 700 |
1 |
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|a van Schaik, Ron H.N.
|e editor.
|
| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
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|t Springer eBooks
|