Pharmacogenomics : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Innocenti, Federico. (Editor ), van Schaik, Ron H.N. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2013.
Edición:2nd ed. 2013.
Colección:Methods in Molecular Biology, 1015
Materias:
Tabla de Contenidos:
  • Pharmacogenomics: Historical Perspective and Current Status
  • Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping
  • Clinical SNP Detection by the SmartAmp Method
  • MALDI-TOF Mass Spectrometry
  • TaqMan® Drug Metabolism Genotyping Assays for the Detection of Human Polymorphisms Involved in Drug Metabolism
  • Pyrosequencing of Clinically Relevant Polymorphisms
  • Pharmacogenetics Using Luminex® xMAP® Technology: Method for Developing a Custom Multiplex Single Nucleotide Polymorphism Mutation Assay
  • Use of Linkage Analysis, Genome-Wide Association Studies, and Next-Generation Sequencing in the Identification of Disease-Causing Mutations
  • The GoldenGate Genotyping Assay: Custom Design, Processing, and Data Analysis
  • Genome-Wide Gene Expression Profiling, Genotyping, and Copy Number Analyses of Acute Myeloid Leukemia Using Affymetrix GeneChips
  • Epigenetic Techniques in Pharmacogenetics
  • Plasmid Derived External Quality Controls for Genetic Testing
  • Allelic Imbalance Assays to Quantify Allele-Specific Gene Expression and Transcription Factor Binding
  • SCAN: A Systems Biology Approach to Pharmacogenomic Discovery
  • Methods to Examine the Impact of Nonsynonymous SNPs on Protein Degradation and Function of Human ABC Transporter
  • In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism
  • In Vitro and In Vivo Mouse Models for Pharmacogenetic Studies
  • The Hydrodynamic Tail Vein Assay as a Tool for the Study of Liver Promoters and Enhancers
  • A Guide to the Current Web-Based Resources in Pharmacogenomics
  • PharmGKB: The Pharmacogenomics Knowledge Base
  • Genetic Databases in Pharmacogenomics: The Frequency of Inherited Disorders Database (FINDbase)
  • Development of Predictive Models for Estimating Warfarin Maintenance Dose Based on Genetic and Clinical Factors
  • Evidence Based Drug Dosing and Pharmacotherapeutic Recommendations Per Genotype.