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170831s2017 xxu| s |||| 0|eng d |
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|a 9781493972449
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| 024 |
7 |
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|a 10.1007/978-1-4939-7244-9
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Prions :
|b Methods and Protocols /
|c edited by Victoria A. Lawson.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2017.
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| 300 |
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|a XI, 371 p. 52 illus., 26 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1658
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| 505 |
0 |
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|a Purification and Fibrillation of Full-length Recombinant PrP -- Method for Folding of Recombinant Prion Protein to Soluble b-sheet Secondary Structure -- Analysis of Prion Protein Conformation using Circular Dichroism Spectroscopy -- Analysis of Prion Protein Structure using Nuclear Magnetic Resonance Spectroscopy -- Immunodetection of PrPSc using Western Immunoblotting Techniques -- Analysis of miRNA Signatures in Neurodegenerative Prion Disease -- Expression of Heterologous PrP and Prion Propagation in RK13 Cells -- Generation of Infectious Prions and Detection with the Prion Infected Cell Assay -- Analysis of Cellular Prion Protein Endoproteolytic Processing -- Cellular Analysis Adult Neural Stem Cells for Investigating Prion Biology -- Neurotoxicity of Prion Peptides on Cultured Cerebellar Neurons -- Methods of Protein Misfolding Cyclic Amplification -- RT-QuIC Assays for Prion Disease Detection and Diagnostics -- A Quick Method to Evaluate the Effect of the Amino Acid Sequence in the Misfolding Proneness of the Prion Protein -- Insights into Mechanisms of Transmission and Pathogenesis from Transgenic Mouse Models of Prion Diseases.- In vivo Near Infrared Imaging of Neurodegeneration -- Strain Typing of Prion Diseases using in vivo Mouse Models -- Preparation and Immunostaining of the Myenteric Plexus of Prion Infected Mice -- Cell Culture Methods for Screening of Prion Therapeutics -- Real-Time Quaking Induced Conversion for Diagnosis of Prion Disease -- Methods for Molecular Diagnosis of Human Prion Disease -- Molecular sub-typing of PrPres in Human Sporadic CJD Brain Tissue -- Intercellular Prion-like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture.
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| 650 |
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0 |
|a Neurosciences.
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| 650 |
1 |
4 |
|a Neurosciences.
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| 700 |
1 |
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|a Lawson, Victoria A.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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