Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications : Proceedings of the 6th International Conference on Sodium Calcium Exchange /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Annunziato, Lucio. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 2013.
Edition:1st ed. 2013.
Series:Advances in Experimental Medicine and Biology, 961
Subjects:
Table of Contents:
  • Part I. Historical Perspective
  • 1. Livin with NCX and Lovin It: 45 Year Romance
  • 2. 20 Years from NCX Purification and Cloning: Milestones
  • Part II Structural and Functional Aspects of NCX
  • 3. Ca2+ Regulation in the Na+/Ca2+ Exchanger Features a Dual Electrostatic Switch Mechanism
  • 4. Molecular Determinants of Allosteric Regulation in NCX Proteins
  • 5. NCX1: Mechanism of Transport
  • 6. Structural Studies of the Ca2+ Regulatory Domain of Drosophila Na+/Ca2+ Exchanger CALX
  • 7. Interplay of Ca2+ and Mg2+ in Sodium-Calcium and in other Ca2+ Binding Proteins. Magnesium: Watchdog That Blocks Each Turn If Able
  • Part III. Structural and Functional Aspects of NCKX
  • 8. Functional and Structural Properties of the NCKX2 Na+-Ca2+/K+ Exchanger: a Comparison with the NCX1 Na+/Ca2+ Exchanger
  • 9. NCKX5, a Natural Regulator of Human Skin Colour Variation Regulates the Expression of Key Pigment Genes mc1r and alpha-MSH, and Alters Cholesterol Homeostasis in Normal Human Melanocytes
  • 10. Expression and Regulation of Sodium/Calcium Exchangers, NCX and NCKX, in Reproductive Tissues: Do They Play a Critical Role in Calcium Transport for Reproduction and Development?
  • Part IV. Genetic and Epigenetic Regulation
  • 11. Transcriptional Pathways and Potential Therapeutic Targets in the Regulation of NCX1 Expression in Cardiac Hypertrophy and Failure
  • 12. Transcriptional Regulation of ncx1 Gene in the Brain
  • Part V. Regulatory Mechanisms of NCX
  • 13. Metabolic Regulation of the Squid Nerve Na+/Ca2+ Exchanger: Recent Developments
  • 14. Regulation of Sodium-Calcium Exchanger Activity by Creatine Kinase
  • 15. Coordinated Regulation of Cardiac Na<+/Ca2+ Exchanger and Na+-K+-ATPase by Phospholemman (FXYD1)
  • Part VI. Subcellular Localization and Function of NCX in Ca2+-Storing Organelles and Mitochondria
  • 16. Mitochondria Na+-Ca2+ Exchange in Cardiomyocytes and Lymphocytes
  • 17. New Insights in Mitochondrial Calcium Handling by Sodium/Calcium Exchanger
  • Part VII. NCX in Neurodegenerative Diseases
  • 18. Genetically-Modified Mice as a Strategy to Unravel the Role Played by the Na+/Ca2+ Exchanger in Brain Ischemia and in Spatial Learning and Memory Deficits
  • 19. NCX as a Key Player in the Neuroprotection Exerted by Ischemic Preconditioning and Postconditioning
  • 20. The Role of the Mitochondrial NCX in the Mechanism of Neurodegeneration in Parkinson's Disease
  • 21. The Contribution of the Sodium-Calcium Exchanger (NCX) and Plasma Membrane Ca2+-ATPase (PMCA) to Cerebellar Synapse Function
  • Part VIII. Emerging Role of NCX Activity in Immune and Glial Cells
  • 22. Sodium-Calcium Exchanger Modulates the L-Glutamate Ca2+-signalling in Type-1 Cerebellar Astrocytes
  • 23. Immunosupressive Drugs, Immunophilins and Functional Expression of NCX Isoforms
  • 24. Calcium Influx Through Reversed ncx Controls Migration Of Microglia
  • 25. Sodium Fluxes and Astroglial Function
  • 26. New Roles of NCX in Glial Cells: Activation Of Microglia in Ischemia and Differentiation of Oligodendrocytes
  • 27. Human Macrophages and Monocytes Express Functional Na+/Ca2+ Exchangers 1 and 3
  • Part IX. NCX in the Hearth and Vascular Smooth Muscle
  • 28. New Insights into the Contribution of Arterial NCX to the Regulation of Myogenic Tone and Blood Pressure
  • 29. Toward an Understanding of the Complete NCX1 Lifetime in the Cardiac Sarcolemma
  • Part X. NCX Role in Hypertension, Heart Failure, Ischemia-Reperfusion, Arrhythmias, and Diabetes
  • 30. Cardiac Sodium-Calcium Exchange and Efficient Excitation-Contraction Coupling: Implications for Heart Disease
  • 31. Cross-talk Between Plasma Membrane Na+/Ca2+ Exchanger-1 and TRPC/ORAI Containing Channels: Key Players in Arterial Hypertension
  • 32. T-tubule Remodeling and Ryanodine Receptor Organization Modulate Sodium-Calcium Exchange
  • 33. Na+/ Ca2+ Exchange and the Plasma Membrane Ca2+-ATPase in β-Cell Function and Diabetes
  • Part XI. NCX Partners in Ionic Homeostasis: ASIC, NMDA, NHE, and TRPC
  • 34. The Na+/H+ Exchanger NHE5 is Sorted to Discrete Intracellular Vesicles in the Central and Peripheral Nervous Systems
  • 35. The Role of Na+/H+ Exchanger Isoform 1 in Inflammatory Responses: Maintaining H+ Homeostasis of Immune Cells
  • 36. Acid-sensing Ion Channels in Pathological Conditions
  • 37. Non-Selective Cation Channels and Links to Hippocampal Ischemia, Aging and Dementia.