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180921s2018 xxu| s |||| 0|eng d |
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|a 9781493987399
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| 024 |
7 |
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|a 10.1007/978-1-4939-8739-9
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Synaptosomes /
|c edited by Kathryn M. Murphy.
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| 250 |
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|a 1st ed. 2018.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2018.
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| 300 |
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|a XV, 312 p. 55 illus., 32 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Neuromethods,
|v 141
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| 505 |
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|a Introduction to Synaptosome Methods and Applications -- Victor P. Whittaker: The Discovery of the Synaptosome and Its Implications -- Synaptosome Preparations: Which Procedure Should I Use? -- Protocol for a High-Throughput Semi-Automated Preparation for Filtered Synaptoneurosomes -- Subcellular Fractionation of Brain Tissue from Small Tissue Explants -- Preparation of P2 of Percoll-Purified Synaptosomes from Mammalian Brain Tissue -- Synaptosomal Bioenergetics and Glutamate Release -- Synaptosomes Bioenergetics and Calcium Handling: Aging Response -- Isolation of Highly Purified and Functionally Active Synaptic Mitochondria -- Affinity Proteomics for Interactome and Phosphoproteome Screening in Synaptosomes -- Manipulating Synapse-Enriched Biochemical Fractions to Detect a Purified Synaptic Protein's Effect on Neurotransmitter Release -- Prosomes: Supramolecular Structures at the Synaptosome Membrane Involved in Vesicle Docking, Fusion, and Neurotransmitter Release -- SMPL-Synaptic Membranes: Nanodisc-Mediated Synaptic Membrane Mimetics Expand the Toolkit for Drug Discovery and the Molecular Cell Biology of Synapses -- Profiling of MicroRNA and Protein from Purified Synaptoneurosomes in a Neurodegenerative Disease Model -- Use of Synaptoneurosome Samples to Study Development and Plasticity of Human Cortex -- The Use of Synaptosomes in Studying Autism Spectrum Disorder and Other Neurodevelopmental Disorders -- Flow Cytometric Evaluation of Crude Synaptosome Preparation as a Way to Study Synaptic Alteration in Neurodegenerative Diseases.
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| 650 |
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|a Neurosciences.
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| 650 |
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4 |
|a Neurosciences.
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| 700 |
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|a Murphy, Kathryn M.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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