Safety and Efficacy of Gene-Based Therapeutics for Inherited Disorders /
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| Format: | eBook |
| Language: | English |
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Cham :
Springer International Publishing : Imprint: Springer,
2017.
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| Edition: | 1st ed. 2017. |
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Table of Contents:
- Overview: gene transfer strategies, principles, applications
- Manufacturing viral gene therapy vectors: general approaches and challenges
- Retrovirus- and lentivirus-based vectors
- Preclinical and clinical applications of retroviral vectors
- Preclinical and clinical applications of lentiviral vectors
- Retrovirus and lentivirus integration
- Adenovirus-based vectors for gene therapy
- Adenoviral vector-host interactions
- Helper-dependent adenoviral vectors
- Gene therapy for cancer treatment
- Oncolytic adenoviruses for cancer treatment
- Vaccination by gene transfer vectors
- AAV vectors: general features and applications
- Adaptive immune response to viral vector delivery
- Herpes viruses: general features and applications
- RNA interference-based strategy for treatment of human diseases
- Antisense oligonucleotide based therapeutics
- Gene editing strategies
- Nonviral vectors.