Snake and Spider Toxins : Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Priel, Avi. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer US : Imprint: Humana, 2020.
Edición:1st ed. 2020.
Colección:Methods in Molecular Biology, 2068
Materias:
Tabla de Contenidos:
  • Snake- and Spider-Venom-Derived Toxins as Lead Compounds for Drug Development
  • Analytics for Bioactivity Profiling of Complex Mixtures with a Focus on Venoms
  • Venom Collection from Spiders and Snakes: Voluntary and Involuntary Extractions (“Milking”) and Venom Gland Extractions
  • Production and Purification of Recombinant Toxins
  • RNA-Sequencing of Snake Venom Glands
  • Exploring Toxin Evolution: Venom Protein Transcript Sequencing and Transcriptome-Guided High-Throughput Proteomics
  • Three-Dimensional Structure Determination of Peptides using Solution Nuclear Magnetic Resonance Spectroscopy
  • Determining the Structures of the Snake and Spider Toxins by X-Rays
  • MALDI-TOF Mass Spectrometric Profiling of Spider Venoms
  • Methods for Evaluation of a Snake Venom Derived Disintegrin in Animal Models of Human Cancer
  • Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists
  • Using C. elegans to Study the Effects of Toxins in Sensory Ion Channels In Vivo
  • Measurements of Cell Death Induced by Snake and Spider’s Venoms and Derived Toxins
  • Using Toxins in Brain Slice Recordings
  • High-Throughput Calcium Imaging Screen of Toxins’ Function in Dissociated Sensory Neurons
  • Synthesizing and Expressing Native Ion Channels.