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131122s2014 xxu| s |||| 0|eng d |
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|a 9781461490999
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| 024 |
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|a 10.1007/978-1-4614-9099-9
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Role of Proteases in Cellular Dysfunction /
|c edited by Naranjan S. Dhalla, Sajal Chakraborti.
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| 250 |
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|a 1st ed. 2014.
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| 260 |
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|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2014.
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| 300 |
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|a XI, 462 p. 58 illus., 46 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Advances in Biochemistry in Health and Disease ;
|v 8
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| 505 |
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|a Part A: Proteases and Neural Disorders.- Role of Calpain in Immunobiology of Neurodegenerative Diseases.- Calpain Interactions with the Protein Phosphatase Calcineurin in Neurodegeneration.- Involvement of Caspases in Neurodegenaration and Stroke.- Matrix Metalloproteinases in Ischemia-Reperfusion Injury in Brain: Antioxidants as Rescuer.- The Role of Matrix Metalloproteinases in Neurovascular Injury.- The Role of Proteases in Embryonic Neural Crest Cells.- Part B: Proteases and Cancer -- Proteases and Cancer Development.- Matrix Metalloproteinase and its Inhibitors in Cancer Progression.- Ubiquitin-Proteosome System in the Hallmarks of Cancer.- Matrix Metalloproteinases in Cancer Metastasis: An unsolved Mystery.- A Disintegrin and Metalloprotease-12 as a New target for Cancer Treatment -- Proteases and Their Role in Drug Development with an Emphasis in Cancer.- Part C: Proteases and Cardiovascular Defects.- Role of Matrix Metalloproteinases in Atherosclerosis.- The Importance of the Urokinase-type Plasminogen Activator (uPA) and its receptor (uPAR) for the Development and Progression of Atherosclerosis.- Matrix Metalloproteinases and Hypertension.- Regulation of Proteolysis in Vascular Remodeling.- Emerging Role of Genetic Variants of Matrix Metalloproteinases Genes in Left Ventricular Dysfunction.- Implications of Intracellular Proteolytic Activation of MMP-2 in the Heart.- Matrix Metalloprotease-2 in the Development and Progression of Cardiovascular Diseases.- Role of Protease Activation in Subcellular Remodeling and Heart Failure.- Proteases as Potential Targets in Left Ventricular Remodeling After Myocardial Infarction.- MMPs in Cardiovascular Diseases: Emerging Pharmacological Targets.- Proteases as Clinical Markers of Adverse Remodeling for Heart Failure in the Aging Population.
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| 650 |
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|a Proteomics.
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| 650 |
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|a Cell physiology.
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| 650 |
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|a Proteins .
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| 650 |
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|a Cancer research.
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| 650 |
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|a Neurosciences.
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| 650 |
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|a Medicine.
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| 650 |
1 |
4 |
|a Proteomics.
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| 650 |
2 |
4 |
|a Cell Physiology.
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| 650 |
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4 |
|a Receptors.
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| 650 |
2 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Neurosciences.
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| 650 |
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4 |
|a Biomedicine, general.
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| 700 |
1 |
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|a Dhalla, Naranjan S.
|e editor.
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| 700 |
1 |
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|a Chakraborti, Sajal.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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