Role of Proteases in Cellular Dysfunction /
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Colección: | Advances in Biochemistry in Health and Disease ;
8 |
| Materias: |
Tabla de Contenidos:
- Part A: Proteases and Neural Disorders.- Role of Calpain in Immunobiology of Neurodegenerative Diseases.- Calpain Interactions with the Protein Phosphatase Calcineurin in Neurodegeneration.- Involvement of Caspases in Neurodegenaration and Stroke.- Matrix Metalloproteinases in Ischemia-Reperfusion Injury in Brain: Antioxidants as Rescuer.- The Role of Matrix Metalloproteinases in Neurovascular Injury.- The Role of Proteases in Embryonic Neural Crest Cells.- Part B: Proteases and Cancer
- Proteases and Cancer Development.- Matrix Metalloproteinase and its Inhibitors in Cancer Progression.- Ubiquitin-Proteosome System in the Hallmarks of Cancer.- Matrix Metalloproteinases in Cancer Metastasis: An unsolved Mystery.- A Disintegrin and Metalloprotease-12 as a New target for Cancer Treatment
- Proteases and Their Role in Drug Development with an Emphasis in Cancer.- Part C: Proteases and Cardiovascular Defects.- Role of Matrix Metalloproteinases in Atherosclerosis.- The Importance of the Urokinase-type Plasminogen Activator (uPA) and its receptor (uPAR) for the Development and Progression of Atherosclerosis.- Matrix Metalloproteinases and Hypertension.- Regulation of Proteolysis in Vascular Remodeling.- Emerging Role of Genetic Variants of Matrix Metalloproteinases Genes in Left Ventricular Dysfunction.- Implications of Intracellular Proteolytic Activation of MMP-2 in the Heart.- Matrix Metalloprotease-2 in the Development and Progression of Cardiovascular Diseases.- Role of Protease Activation in Subcellular Remodeling and Heart Failure.- Proteases as Potential Targets in Left Ventricular Remodeling After Myocardial Infarction.- MMPs in Cardiovascular Diseases: Emerging Pharmacological Targets.- Proteases as Clinical Markers of Adverse Remodeling for Heart Failure in the Aging Population.