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131129s2014 ne | s |||| 0|eng d |
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|a 9789400777262
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| 024 |
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|a 10.1007/978-94-007-7726-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Tumor Dormancy, Quiescence, and Senescence, Volume 2 :
|b Aging, Cancer, and Noncancer Pathologies /
|c edited by M.A. Hayat.
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| 250 |
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|a 1st ed. 2014.
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| 260 |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2014.
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| 300 |
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|a XXVII, 320 p. 49 illus., 33 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
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|a Tumor Dormancy and Cellular Quiescence and Senescence, Aging, Cancer, and Noncancer Pathologies ;
|v 2
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| 505 |
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|a Preface. I Molecular Mechanisms -- Asymmetric Dimethylarginine Accelerates Cellular Senescence -- Membrane-Derived Extracellular Vesicles from Endothelial Progenitor Cells Activate Angiogenesis -- Induction of P21-Dependent Senescence: Role of NAE Inhibitor MLN4924 -- Regulation of the Novel Senescence Pathway by SKP2 E3 Ligase -- Oncogene-Induced Senescence: Role of Mitochondrial Dysfunction -- Interleukin- 6 induces Premature Senescence Involving Signal Transducer and Activator of Transcription 3 and Insulin-Like Growth Factor-Binding Protein 5 -- A Role for the Nuclear Lamina Shape in Cell Senescence and Aging -- Upregulation of Alpha-2-Macroglobulin in Replicative Senescence -- Elevation of Ceramide in Senescence: Role of Sphingolipid Metabolism -- Molecular Signals Underlying Hair Follicle Morphagenesis and Cutaneous Regeneration -- Role of Chromatin -Remodeling Factor Jun Dimerization Protein 2 (JDP2) in Cellular Senescence -- Induction of Cellular Senescence: Role of Mitogen-Activated Protein Kinase-Interacting Kinase 1 -- Mechanisms of Premature Cell Senescence. II Tumor And Cancer -- Nuclear Protein Pirin Negates the Cellular Senescence Barrier Against Cancer Development -- Defects in Chromatin Structure and Diseases -- The Role of Fibrosis in Tumor Progression and the Dormant to Proliferative Switch -- Diagnosis of Branchial Cyst Carcinoma: Role of Stem Cells and Dormancy -- Function of ING Proteins in Cancer and Senescence -- Premalignancy and Cellular Senescence -- Loss of CDH1 Triggers Premature Senescence in Part Via Activation of Both the RB/E2F1 and the Claspin/CHK1/P53 Tumor Suppressor Pathways -- Suppression of Premature Senescence and Promotion of Metastatic Transformation: Role of Reduced TGF-Beta Signaling in Human Cancer Progression -- Senescence Escape in Melanoma: Role of Spleen Tyrosine Kinase SYK -- Micrometastatic Cancer Cells: Role of Tumor Dormancy in Non-Small Cell Lung Cancer. III Quiescent Cd4+ T Cells Inhibit Multiples Stages Of Hiv Infection Stem Cells And Cancer Stem Cells -- Senescent-Derived Pluripotent Stem Cells are able to Redifferentiate into Fully Rejuvenated Cells -- The Transcription Factor Gata2 Regulates Quiescence in Haematopoietic Stem and Progenitor Cells -- Dormancy and Recurrence of Cancer Stem Cells in Bone: Role of Bone Morphogenetic Proteins -- Role of Microenvironment in Regulating Stem Cell and Tumor Initiating Cancer Cell Behavior and its Potential Therapeutic Implications -- Index.
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| 650 |
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|a Life sciences.
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| 650 |
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|a Medicine.
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| 650 |
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|a Life Sciences, general.
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| 650 |
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|a Biomedicine, general.
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| 650 |
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|a Medicine/Public Health, general.
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| 700 |
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|a Hayat, M.A.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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