|
|
|
|
| LEADER |
01938nam a22003255i 4500 |
| 001 |
000292147 |
| 005 |
20210921171751.0 |
| 007 |
cr nn 008mamaa |
| 008 |
151208s2015 gw | s |||| 0|eng d |
| 020 |
|
|
|a 9783319260884
|
| 024 |
7 |
|
|a 10.1007/978-3-319-26088-4
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 100 |
1 |
|
|a Bross, Peter.
|e author.
|
| 245 |
1 |
4 |
|a The Hsp60 Chaperonin /
|c by Peter Bross.
|
| 250 |
|
|
|a 1st ed. 2015.
|
| 260 |
# |
# |
|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2015.
|
| 300 |
|
|
|a XV, 85 p. 19 illus., 4 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Protein Folding and Structure,
|
| 505 |
0 |
|
|a Introduction -- Historical sketch of the discovery and recognition of the function of chaperonins -- Molecular structure of chaperonins -- Folding by enclosure in the chaperonin cavity -- Evolutionary origins and family relations -- Chaperoning mechanisms: folding helpers, folding protectors or misfolding blockers? -- Sequence variations in proteins affecting chaperonin dependence -- Genetic organization of type I chaperonin genes -- Regulation of type I chaperonin gene expression -- Subcellular localization -- Posttranslational modifications -- Variations in Hsp60 and Hsp10 in humans -- Type I chaperonins are essential for cell viability and mutations cause deficiency phenotypes -- Human diseases caused by genetic mutations in the Hsp60/Hsp10 system -- Molecular investigations of disease mechanisms -- Molecular investigations of disease mechanisms -- Outlook.
|
| 650 |
|
0 |
|a Proteins .
|
| 650 |
|
0 |
|a Bioorganic chemistry.
|
| 650 |
|
0 |
|a Molecular biology.
|
| 650 |
1 |
4 |
|a Protein Science.
|
| 650 |
2 |
4 |
|a Bioorganic Chemistry.
|
| 650 |
2 |
4 |
|a Molecular Medicine.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|