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02715nam a22003135i 4500 |
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20210614151650.0 |
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cr nn 008mamaa |
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110711s2011 xxu| s |||| 0|eng d |
| 020 |
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|a 9781617791888
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| 024 |
7 |
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|a 10.1007/978-1-61779-188-8
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Therapeutic Oligonucleotides :
|b Methods and Protocols /
|c edited by John Goodchild.
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| 250 |
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|a 1st ed. 2011.
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| 260 |
# |
# |
|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2011.
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| 300 |
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|a XI, 340 p. 70 illus. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 764
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| 505 |
0 |
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|a Therapeutic Oligonucleotides -- Dinucleotides Containing 3¢-S-Phosphorothiolate Linkages -- 2'-O,4'-C-Methyleneoxymethylene Bridged Nucleic Acids (2',4'-BNACOC) -- A Non-covalent Peptide-based Strategy for Ex-vivo and In vivo Oligonucleotide Delivery -- Cell Penetrating Peptides-based Strategies for the Delivery of Splice Redirecting Antisense Oligonucleotides -- A Nanoparticle for Tumor Targeted Delivery of Oligomers -- Light-directed Delivery of Nucleic Acids -- Antibody Targeted siRNA Delivery -- Aptamer-Drug Conjugation for Targeted Tumor Cell Therapy -- Five-step Process for Screening Antisense Compounds for Efficacy: Gene Target IL-12Rb2 -- Diverse Small Non-coding RNAs in RNA Interference Pathways -- Quantification of siRNAs In vitro and In vivo -- Optimization of Transfection Conditions and Analysis of siRNA Potency Using Real-time PCR -- siRNA Knockdown of Gene Expression in Endothelial Cells -- Using RNA Interference in Schistosoma mansoni -- Performing the Labeled microRNA Pull-down (LAMP) Assay System: An Experimental Approach for High-throughput Identification of microRNA-target mRNAs -- Synthesis, Purification, and Characterization of Oligoribonucleotides that Act as Agonists of TLR7 and/or TLR8 -- Synthesis, Purification, and Characterization of Immune-Modulatory Oligodeoxynucleotides that Act as Agonists of Toll-like Receptor 9 -- Surface Plasmon Resonance Investigation of RNA Aptamer-RNA Ligand Interactions -- Practical Considerations for Analyzing Antigene RNAs (agRNAs): RNA Immunoprecipitation of Argonaute Protein -- Inhibition of Human Papillomavirus Expression Using DNAzymes.
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| 650 |
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0 |
|a Biochemistry.
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| 650 |
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0 |
|a Nucleic acids.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Nucleic Acid Chemistry.
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| 700 |
1 |
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|a Goodchild, John.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|