Therapeutic Oligonucleotides : Methods and Protocols /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Goodchild, John. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edition:1st ed. 2011.
Series:Methods in Molecular Biology, 764
Subjects:
Table of Contents:
  • Therapeutic Oligonucleotides
  • Dinucleotides Containing 3¢-S-Phosphorothiolate Linkages
  • 2'-O,4'-C-Methyleneoxymethylene Bridged Nucleic Acids (2',4'-BNACOC)
  • A Non-covalent Peptide-based Strategy for Ex-vivo and In vivo Oligonucleotide Delivery
  • Cell Penetrating Peptides-based Strategies for the Delivery of Splice Redirecting Antisense Oligonucleotides
  • A Nanoparticle for Tumor Targeted Delivery of Oligomers
  • Light-directed Delivery of Nucleic Acids
  • Antibody Targeted siRNA Delivery
  • Aptamer-Drug Conjugation for Targeted Tumor Cell Therapy
  • Five-step Process for Screening Antisense Compounds for Efficacy: Gene Target IL-12Rb2
  • Diverse Small Non-coding RNAs in RNA Interference Pathways
  • Quantification of siRNAs In vitro and In vivo
  • Optimization of Transfection Conditions and Analysis of siRNA Potency Using Real-time PCR
  • siRNA Knockdown of Gene Expression in Endothelial Cells
  • Using RNA Interference in Schistosoma mansoni
  • Performing the Labeled microRNA Pull-down (LAMP) Assay System: An Experimental Approach for High-throughput Identification of microRNA-target mRNAs
  • Synthesis, Purification, and Characterization of Oligoribonucleotides that Act as Agonists of TLR7 and/or TLR8
  • Synthesis, Purification, and Characterization of Immune-Modulatory Oligodeoxynucleotides that Act as Agonists of Toll-like Receptor 9
  • Surface Plasmon Resonance Investigation of RNA Aptamer-RNA Ligand Interactions
  • Practical Considerations for Analyzing Antigene RNAs (agRNAs): RNA Immunoprecipitation of Argonaute Protein
  • Inhibition of Human Papillomavirus Expression Using DNAzymes.