The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy /

Detalles Bibliográficos
Autores principales: Rüb, Udo. (Autor), Vonsattel, Jean Paul G. (Autor), Heinsen, Helmut. (Autor), Korf, Horst-Werner. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Anatomy, Embryology and Cell Biology, 217
Materias:
Tabla de Contenidos:
  • 1. Introduction
  • 2. The neuropathological grading of Huntington disease
  • 3. The cerebral cortex in Huntington´s disease
  • 4. Degeneration of select motor and limbic nuclei of the thalamus in Huntington’s disease
  • 5. Consistent and widespread degeneration of the cerebellum in Huntington’s disease
  • 6. Elucidation of the role of the premotor oculomotor brainstem nuclei in the pathogenesis of oculomotor dysfunctions in Huntington’s disease
  • 7. Widespread brainstem neurodegeneration in Huntington’s disease
  • 8. Intraneuronal transport and defense mechanisms with possible pathogenetic relevance in Huntington’s disease
  • 9. The disease protein huntingtin and neuronal protein aggregations in Huntington’s disease
  • 10. Pathological nerve cell alterations in Huntington’s disease (HD) and their possible role for the demise of nerve cells
  • 11. Conclusions and outlook.