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02745nam a22003015i 4500 |
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20211008103848.0 |
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cr nn 008mamaa |
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161125s2017 xxu| s |||| 0|eng d |
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|a 9781493966615
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| 024 |
7 |
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|a 10.1007/978-1-4939-6661-5
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a Stem Cell-Derived Models in Toxicology /
|c edited by Mike Clements, Liz Roquemore.
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| 250 |
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|a 1st ed. 2017.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2017.
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| 300 |
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|a XII, 341 p. 124 illus., 108 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Pharmacology and Toxicology,
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| 505 |
0 |
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|a Stem Cell‐Derived Models for Safety and Toxicity Assessments: Present and Future Studies in the “Proclinical Space” -- Human Pluripotent Stem Cell Test for Assessing the Potential Teratogen Risk -- Cardiac Action Potential Measurement in Human Embryonic Stem Cell Cardiomyocytes for Cardiac Safety Studies Using Manual Patch-Clamp Electrophysiology -- Automated Patch Clamp Recordings of Human Stem Cell-Derived Cardiomyocytes -- The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential -- Optogenetic Approach to Cardiotoxicity Screening: Simultaneous Voltage and Calcium Imaging Under Paced Conditions -- HTS Compatible Voltage- and Ca2+-Sensitive Dye Recordings from hiPSC-Derived Cardiomyocytes Using the Hamamatsu FDSS Systems -- Kinetic Image Cytometry for Predicting Arrhythmias Using Human Stem Cell-Derived Cardiomyocytes -- Decoding Ca2+ Signals as a Non-Electrophysiological Method for Assessing Drug Toxicity in Stem-Cell Derived Cardiomyocytes -- Combined Impedance and Extracellular Field Potential Recordings from Human Stem Cell-Derived Cardiomyocytes -- Edge Detection for Contractility Measurements with Cardiac Spheroids -- Contractile Force Readout of hESC-Cardiomyocytes -- In Vitro Cardiotoxicity Investigation Using High Content Analysis and Human Stem Cell-Derived Models -- Structural Toxicity: Hypertrophy Models of Human Pluripotent Stem Cell-Derived Cardiomyocytes -- Addressing Functional Neurotoxicity Using the Microelectrode Array (MEA) -- Micropatterned Co-Cultures of Induced Pluripotent Stem Cell-Derived Hepatocytes and Stromal Cells for Drug Toxicity Studies.
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| 650 |
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|a Pharmacology.
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| 650 |
1 |
4 |
|a Pharmacology/Toxicology.
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| 700 |
1 |
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|a Clements, Mike.
|e editor.
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| 700 |
1 |
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|a Roquemore, Liz.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
|