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02780nam a22003135i 4500 |
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130217s2013 xxu| s |||| 0|eng d |
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|a 9781627032995
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024 |
7 |
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|a 10.1007/978-1-62703-299-5
|2 doi
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040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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245 |
1 |
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|a Systems Metabolic Engineering :
|b Methods and Protocols /
|c edited by Hal S. Alper.
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250 |
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|a 1st ed. 2013.
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260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2013.
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300 |
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|a XII, 474 p. 61 illus., 47 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Methods in Molecular Biology,
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505 |
0 |
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|a Genome-Scale Model Management and Comparison -- Automated Genome Annotation and Metabolic Model Reconstruction in the SEED and Model SEED -- Metabolic Model Refinement Using Phenotypic Microarray Data -- Linking Genome-Scale Metabolic Modeling and Genome Annotation -- Resolving Cell Composition through Simple Measurements, Genome-Scale Modeling, and a Genetic Algorithm -- A Guide to Integrating Transcriptional Regulatory and Metabolic Networks Using PROM (Probabilistic Regulation of Metabolism) -- Kinetic Modeling of Metabolic Pathways: Application to Serine Biosynthesis -- Computational Tools for Guided Discovery and Engineering of Metabolic Pathways -- Retrosynthetic Design of Heterologous Pathways -- Customized Optimization of Metabolic Pathways by Combinatorial Transcriptional Engineering -- Adaptive Laboratory Evolution for Strain Engineering -- Trackable Multiplex Recombineering for Gene-Trait Mapping in E. coli -- Identification of Mutations in Evolved Bacterial Genomes -- Discovery of Post-Transcriptional Regulatory RNAs Using Next Generation Sequencing Technologies -- 13C-based Metabolic Flux Analysis: Fundamentals and Practice -- Nuclear Magnetic Resonance Methods for Metabolic Fluxomics -- Using Multiple Tracers for 13C Metabolic Flux Analysis -- Isotopically Nonstationary 13C Metabolic Flux Analysis -- Sample Preparation and Biostatistics for Integrated Genomics Approaches -- Targeted Metabolic Engineering Guided by Computational Analysis of Single Nucleotide Polymorphisms (SNPs) -- Linking RNA Measurements and Proteomics with Genome-Scale Models -- Comparative Transcriptome Analysis for Metabolic Engineering -- Merging Multiple Omics Datasets In Silico: Statistical Analyses and Data Interpretation.
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650 |
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|a Biotechnology.
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650 |
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|a Metabolism.
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650 |
1 |
4 |
|a Biotechnology.
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650 |
2 |
4 |
|a Microengineering.
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650 |
2 |
4 |
|a Metabolomics.
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700 |
1 |
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|a Alper, Hal S.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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