T Lymphocytes as Tools in Diagnostics and Immunotoxicology /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Martin, Stefan F. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Basel : Springer Basel : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Experientia Supplementum, 104
Materias:
Tabla de Contenidos:
  • The use of T cells in Hazard Characterization of Chemical and Drug Allergens and integration in testing strategies
  • Activation of the TCR complex by peptide-MHC and superantigens
  • Activation of the TCR complex by small chemical compounds
  • T Cell Responses to Contact Allergens
  • Contact hypersensitivity: Quantitative aspects, susceptibility and risk factors
  • Tools and methods for identification and analysis of rare antigen-specific T lymphocytes
  • Human T cell priming assay. Depletion of peripheral blood lymphocytes in CD25+ cells improves the in vitro detection of weak allergen-specific T cells
  • Correlation of contact sensitizer potency with T cell frequency and TCR repertoire diversity
  • On the role of co-inhibitory molecules in dendritic cell - T helper cell co-culture assays aimed to detect chemical induced contact allergy
  • T cell responses to drugs and drug metabolites
  • Hypersensitivity reactions to betalactams.