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100301s2006 xxu| s |||| 0|eng d |
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|a 9780387338279
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| 024 |
7 |
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|a 10.1007/0-387-33827-6
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Selenium :
|b Its Molecular Biology and Role in Human Health /
|c edited by Dolph L. Hatfield, Marla J. Berry, Vadim N. Gladyshev.
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| 250 |
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|a 2nd ed. 2006.
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| 260 |
# |
# |
|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 2006.
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| 300 |
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|a XXIV, 420 p. 72 illus. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 505 |
0 |
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|a Selenium: A historical perspective -- Selenium: A historical perspective -- Biosynthesis of selenocysteine and its incorporation into protein -- Selenium metabolism in prokaryotes -- Mammalian and other eukaryotic selenocysteine tRNAs -- Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization -- SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs -- SECIS binding proteins and eukaryotic selenoprotein synthesis -- The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis -- Selenocysteine biosynthesis and incorporation may require supramolecular complexes -- Selenium-containing proteins -- Selenoproteins and selenoproteomes -- Deletion of selenoprotein P gene in the mouse -- Selenium and methionine sulfoxide reduction -- Selenoprotein W in development and oxidative stress -- The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer -- Regulation of glutathione peroxidase-1 expression -- Selenoproteins of the glutathione system -- New roles of glutathione peroxidase-1 in oxidative stress and diabetes -- Selenoproteins of the thioredoxin system -- Mitochondrial and cytosolic thioredoxin reductase knockout mice -- Selenium, deiodinases and endocrine function -- Biotechnology of selenocysteine -- Selenium and human health -- Selenium, selenoproteins and brain function -- Selenium as a cancer preventive agent -- Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium -- Genetic variation among selenoprotein genes and cancer -- Selenium and viral infections -- Role of selenium in HIV/AIDS -- Effects of selenium on immunity and aging -- Selenium and male reproduction -- Mouse models for assessing the role of selenoproteins in health and development -- Drosophila as a tool for studying selenium metabolism and role of selenoproteins -- Selenoproteins in parasites -- Incorporating ‘omics’ approaches to elucidate the role of selenium and selenoproteins in cancer prevention -- Selenium-induced apoptosis -- Selenoprotein mimics -- Update of human dietary standards for selenium.
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| 650 |
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0 |
|a Cancer research.
|
| 650 |
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0 |
|a Biochemistry.
|
| 650 |
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0 |
|a Medical biochemistry.
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| 650 |
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0 |
|a Immunology.
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| 650 |
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0 |
|a Oncology .
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| 650 |
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0 |
|a Nutrition .
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| 650 |
1 |
4 |
|a Cancer Research.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Medical Biochemistry.
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| 650 |
2 |
4 |
|a Immunology.
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| 650 |
2 |
4 |
|a Oncology.
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| 650 |
2 |
4 |
|a Nutrition.
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| 700 |
1 |
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|a Hatfield, Dolph L.
|e editor.
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| 700 |
1 |
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|a Berry, Marla J.
|e editor.
|
| 700 |
1 |
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|a Gladyshev, Vadim N.
|e editor.
|
| 710 |
2 |
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|a SpringerLink (Online service)
|
| 773 |
0 |
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|t Springer eBooks
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