Selenium : Its Molecular Biology and Role in Human Health /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hatfield, Dolph L. (Editor ), Berry, Marla J. (Editor ), Gladyshev, Vadim N. (Editor )
Formato: eBook
Lenguaje:English
Publicado: New York, NY : Springer US : Imprint: Springer, 2006.
Edición:2nd ed. 2006.
Materias:
Tabla de Contenidos:
  • Selenium: A historical perspective
  • Selenium: A historical perspective
  • Biosynthesis of selenocysteine and its incorporation into protein
  • Selenium metabolism in prokaryotes
  • Mammalian and other eukaryotic selenocysteine tRNAs
  • Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization
  • SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs
  • SECIS binding proteins and eukaryotic selenoprotein synthesis
  • The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis
  • Selenocysteine biosynthesis and incorporation may require supramolecular complexes
  • Selenium-containing proteins
  • Selenoproteins and selenoproteomes
  • Deletion of selenoprotein P gene in the mouse
  • Selenium and methionine sulfoxide reduction
  • Selenoprotein W in development and oxidative stress
  • The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer
  • Regulation of glutathione peroxidase-1 expression
  • Selenoproteins of the glutathione system
  • New roles of glutathione peroxidase-1 in oxidative stress and diabetes
  • Selenoproteins of the thioredoxin system
  • Mitochondrial and cytosolic thioredoxin reductase knockout mice
  • Selenium, deiodinases and endocrine function
  • Biotechnology of selenocysteine
  • Selenium and human health
  • Selenium, selenoproteins and brain function
  • Selenium as a cancer preventive agent
  • Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium
  • Genetic variation among selenoprotein genes and cancer
  • Selenium and viral infections
  • Role of selenium in HIV/AIDS
  • Effects of selenium on immunity and aging
  • Selenium and male reproduction
  • Mouse models for assessing the role of selenoproteins in health and development
  • Drosophila as a tool for studying selenium metabolism and role of selenoproteins
  • Selenoproteins in parasites
  • Incorporating ‘omics’ approaches to elucidate the role of selenium and selenoproteins in cancer prevention
  • Selenium-induced apoptosis
  • Selenoprotein mimics
  • Update of human dietary standards for selenium.