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160915s2016 gw | s |||| 0|eng d |
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|a 9783319412832
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| 024 |
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|a 10.1007/978-3-319-41283-2
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
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|a Selenium :
|b Its Molecular Biology and Role in Human Health /
|c edited by Dolph L. Hatfield, Ulrich Schweizer, Petra A. Tsuji, Vadim N. Gladyshev.
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| 250 |
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|a 4th ed. 2016.
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| 260 |
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a XXXI, 628 p. 88 illus., 59 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Part I. The machinery of selenoprotein biosynthesis -- 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis -- 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro -- 3 Probing selenoprotein translation by ribosome profiling -- 4 Pathways in de novo biosynthesis of selenocysteine and cysteine in eukaryotes -- 5 Prokaryotic selenoprotein biosynthesis and function -- 6 The role of selenium in human evolution -- 7 The chemistry of selenocysteine in proteins -- 8 Evolution of selenophosphate synthetase -- 9 Structure and mechanism of selenocysteine synthases -- 10 Mechanism, structure, and biological role of selenocysteine lyase -- Part II. Selenoproteins, their occurrence and function -- 11 Eukaryotic selenoproteomes -- 12 Prokaryotic selenoproteins and selenoproteomes -- 13 Functional genomics of selenoproteins and Se-responsive pathways -- 14 Selenium regulation of the selenoprotein and non-selenoprotein transcriptomes in a variety of species -- 15 77Se NMR spectroscopy of selenoproteins -- 16 Thioredoxin reductase 1 as an anticancer drug target -- 17 Basics and news on glutathione peroxidases -- 18 Glutathione Peroxidase 4 -- 19 The 15 kDa Selenoprotein: Insights into its regulation and function -- 20 Selenoprotein K and protein palmitoylation in regulating immune cell functions -- 21 Selenoprotein M: Structure, expression and functional relevance -- 22 Selenoprotein P and selenium distribution in mammals -- 23 Selenoprotein T: From discovery to functional studies using conditional knockout mice -- 24 Biochemistry and function of methionine sulfoxide reductase -- Part III. Dietary selenium and its impact on human health -- 25 Selenium: Dietary sources, human nutritional requirements and intake across populations -- 26 Human clinical trials involving selenium -- 27 Status of dietary selenium in cancer prevention -- 28 Selenium in HIV/AIDS -- 29 Genetic variations in the genes for selenoproteins implicate the encoded proteins in cancer etiology -- 30 Is adequate selenium important for healthy human pregnancy? -- 31 The epidemiology of selenium and human health -- 32 Sex-specific differences in biological effects and metabolism of selenium -- 33 Selenium and endocrine tissues -- 34 Selenium antagonism with mercury and arsenic: from chemistry to population health and demography -- 35 Biological selenium species and selenium speciation in biological samples -- 36 Selenoproteins in nervous system development, function and degeneration -- 37 Interplay of selenoproteins and different antioxidant systems in various cancers -- 38 Glutathione peroxidase 2, a selenoprotein exhibiting a dual personality in preventing and promoting cancer -- 39 Selenoproteins in cardiovascular redox pathology -- 40 What do we know about selenium contributions to muscle physiology? -- 41 Tissue-specific regulation of thyroid status by selenodeiodinases -- 42 The role of selenoproteins in resolution of inflammation -- 43 Glutathione peroxidase 4 and ferroptosis -- 44 Mutations in humans that adversely affect the selenoprotein synthesis pathway -- 45 Alteration of selenoprotein expression during stress and in aging -- Part V. Biological models for elucidating the role of selenium and selenoproteins in biology and medicine -- 46 Selenocysteine tRNA[Ser]Sec mouse models for elucidating roles of selenoproteins in health and development -- 47 Mouse models that target individual selenoproteins -- 48 The naked mole rat and selenium -- 49 Glutathione peroxidase 1: Models for diabetes and obesity -- 50 Selenium in livestock and other domestic animals.
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| 650 |
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|a Immunology.
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| 650 |
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|a Nutrition .
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| 650 |
1 |
4 |
|a Immunology.
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| 650 |
2 |
4 |
|a Nutrition.
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| 700 |
1 |
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|a Hatfield, Dolph L.
|e editor.
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| 700 |
1 |
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|a Schweizer, Ulrich.
|e editor.
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| 700 |
1 |
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|a Tsuji, Petra A.
|e editor.
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| 700 |
1 |
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|a Gladyshev, Vadim N.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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