Selenium : Its Molecular Biology and Role in Human Health /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hatfield, Dolph L. (Editor ), Schweizer, Ulrich. (Editor ), Tsuji, Petra A. (Editor ), Gladyshev, Vadim N. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:4th ed. 2016.
Materias:
Tabla de Contenidos:
  • Part I. The machinery of selenoprotein biosynthesis
  • 1 Selenocysteine tRNA[Ser]Sec: From nonsense suppressor tRNA to the quintessential constituent in selenoprotein biosynthesis
  • 2 Eukaryotic mechanisms of selenocysteine translation and its reconstitution in vitro
  • 3 Probing selenoprotein translation by ribosome profiling
  • 4 Pathways in de novo biosynthesis of selenocysteine and cysteine in eukaryotes
  • 5 Prokaryotic selenoprotein biosynthesis and function
  • 6 The role of selenium in human evolution
  • 7 The chemistry of selenocysteine in proteins
  • 8 Evolution of selenophosphate synthetase
  • 9 Structure and mechanism of selenocysteine synthases
  • 10 Mechanism, structure, and biological role of selenocysteine lyase
  • Part II. Selenoproteins, their occurrence and function
  • 11 Eukaryotic selenoproteomes
  • 12 Prokaryotic selenoproteins and selenoproteomes
  • 13 Functional genomics of selenoproteins and Se-responsive pathways
  • 14 Selenium regulation of the selenoprotein and non-selenoprotein transcriptomes in a variety of species
  • 15 77Se NMR spectroscopy of selenoproteins
  • 16 Thioredoxin reductase 1 as an anticancer drug target
  • 17 Basics and news on glutathione peroxidases
  • 18 Glutathione Peroxidase 4
  • 19 The 15 kDa Selenoprotein: Insights into its regulation and function
  • 20 Selenoprotein K and protein palmitoylation in regulating immune cell functions
  • 21 Selenoprotein M: Structure, expression and functional relevance
  • 22 Selenoprotein P and selenium distribution in mammals
  • 23 Selenoprotein T: From discovery to functional studies using conditional knockout mice
  • 24 Biochemistry and function of methionine sulfoxide reductase
  • Part III. Dietary selenium and its impact on human health
  • 25 Selenium: Dietary sources, human nutritional requirements and intake across populations
  • 26 Human clinical trials involving selenium
  • 27 Status of dietary selenium in cancer prevention
  • 28 Selenium in HIV/AIDS
  • 29 Genetic variations in the genes for selenoproteins implicate the encoded proteins in cancer etiology
  • 30 Is adequate selenium important for healthy human pregnancy?
  • 31 The epidemiology of selenium and human health
  • 32 Sex-specific differences in biological effects and metabolism of selenium
  • 33 Selenium and endocrine tissues
  • 34 Selenium antagonism with mercury and arsenic: from chemistry to population health and demography
  • 35 Biological selenium species and selenium speciation in biological samples
  • 36 Selenoproteins in nervous system development, function and degeneration
  • 37 Interplay of selenoproteins and different antioxidant systems in various cancers
  • 38 Glutathione peroxidase 2, a selenoprotein exhibiting a dual personality in preventing and promoting cancer
  • 39 Selenoproteins in cardiovascular redox pathology
  • 40 What do we know about selenium contributions to muscle physiology?
  • 41 Tissue-specific regulation of thyroid status by selenodeiodinases
  • 42 The role of selenoproteins in resolution of inflammation
  • 43 Glutathione peroxidase 4 and ferroptosis
  • 44 Mutations in humans that adversely affect the selenoprotein synthesis pathway
  • 45 Alteration of selenoprotein expression during stress and in aging
  • Part V. Biological models for elucidating the role of selenium and selenoproteins in biology and medicine
  • 46 Selenocysteine tRNA[Ser]Sec mouse models for elucidating roles of selenoproteins in health and development
  • 47 Mouse models that target individual selenoproteins
  • 48 The naked mole rat and selenium
  • 49 Glutathione peroxidase 1: Models for diabetes and obesity
  • 50 Selenium in livestock and other domestic animals.