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161201s2016 gw | s |||| 0|eng d |
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|a 9783319445342
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024 |
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|a 10.1007/978-3-319-44534-2
|2 doi
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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|a Systems Pharmacology and Pharmacodynamics /
|c edited by Donald E. Mager, Holly H.C. Kimko.
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250 |
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|a 1st ed. 2016.
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260 |
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2016.
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300 |
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|a XIII, 511 p. 113 illus., 57 illus. in color. :
|b online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a AAPS Advances in the Pharmaceutical Sciences Series,
|v 23
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505 |
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|a Role of Systems Modeling in Regulatory Drug Approval -- Quantitative Systems Pharmacology: Applications and Adoption in Drug Development -- Systems Pharmacology: An Overview -- Discrete dynamic modeling: a network approach for systems pharmacology -- Kinetic Models of Biochemical Signaling Networks -- Mechanistic Models of Physiological Control Systems -- Foundations of Pharmacodynamic Systems Analysis -- Direct, Indirect, and Signal Transduction Response Modeling -- Irreversible Pharmacodynamics -- Feedback Control Indirect Response Models -- Nonlinear Mixed Effects Modeling in Systems Pharmacology -- Detecting Pharmacokinetic and Pharmacodynamic Covariates From High-Dimensional Data -- Multi-Scale Modeling of Drug Action in the Nervous System -- Mechanistic Modeling of Inflammation -- Systems Pharmacology of Tyrosine Kinase Inhibitor-Associated Toxicities -- Translational Modeling of Antibacterial Agents -- Viral Dynamic Modeling of Hepatitis C Virus Infection: Past Successes and Future Challenges -- Using Systems Pharmacology to Advance Oncology Drug Development -- Systems Pharmacology Modeling in Type 2 Diabetes Mellitus.
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650 |
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|a Pharmaceutical technology.
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650 |
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|a Biomathematics.
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650 |
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|a Medical biochemistry.
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650 |
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4 |
|a Pharmaceutical Sciences/Technology.
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650 |
2 |
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|a Mathematical and Computational Biology.
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650 |
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|a Medical Biochemistry.
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700 |
1 |
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|a Mager, Donald E.
|e editor.
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700 |
1 |
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|a Kimko, Holly H.C.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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