|
|
|
|
| LEADER |
02586nam a22003855i 4500 |
| 001 |
000294528 |
| 005 |
20210617083759.0 |
| 007 |
cr nn 008mamaa |
| 008 |
141013s2014 ne | s |||| 0|eng d |
| 020 |
|
|
|a 9789401790789
|
| 024 |
7 |
|
|a 10.1007/978-94-017-9078-9
|2 doi
|
| 040 |
|
|
|a Sistema de Bibliotecas del Tecnológico de Costa Rica
|
| 245 |
1 |
0 |
|a Translation and Its Regulation in Cancer Biology and Medicine /
|c edited by Armen Parsyan.
|
| 250 |
|
|
|a 1st ed. 2014.
|
| 260 |
# |
# |
|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2014.
|
| 300 |
|
|
|a XXXIV, 697 p. 52 illus., 44 illus. in color. :
|b online resource.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 505 |
0 |
|
|a Preface -- Introduction -- PART I. TRANSALATION MACHINERY IN CANCER -- Mechanism of Translation in Eukaryotes -- Diverse Mechanisms of Translation Regulation and Their Role in Cancer -- eIF4E and Its Binding Proteins -- RNA Helicases and Their Cofactors -- PDCD4 -- eIF4G -- eIF3 -- The eIF2 Complex and eIF2α -- eIF5A -- eIF6 -- Translation Elongation -- Ribosomes -- Current and Emerging Therapies Targeting Translation -- PART II. REGULATION OF TRANSLATION BY SIGNALING PATHWAYS IN CANCER -- mTOR and Regulation of Translation -- Ribosomal Protein S6 and S6 Kinases -- eIF4E Phosphorylation Downstream of MAPK Pathway -- PART III. CELL FATE AND TRANSLATION IN CANCER -- Translational Control of Cell Proliferation and Viability in Normal and Neoplastic Cells -- Translation and Apoptosis in Cancer -- Translation in Cancer at Hypoxia -- PART IV. TRANSLATION AND ITS REGULATION BY CANCER TYPES -- Melanoma and Non-Melanoma Skin Cancers -- Sarcomas -- Hematological Malignancies and Premalignant Conditions -- Brain Tumors -- Head and Neck Cancers -- Breast Cancer -- Cancers of the Respiratory System -- Gastric and Esophageal Cancers -- Colorectal Cancers -- Hepatic, Pancreatic and Biliary Cancers -- Pancreatic Neuroendocrine Tumors -- Gynecologic Cancers -- Prostate Cancer -- Cancers of the Urinary System -- List of Abbreviations.
|
| 650 |
|
0 |
|a Cancer research.
|
| 650 |
|
0 |
|a Oncology .
|
| 650 |
|
0 |
|a Cell biology.
|
| 650 |
|
0 |
|a Molecular biology.
|
| 650 |
|
0 |
|a Biochemistry.
|
| 650 |
|
0 |
|a Medicine.
|
| 650 |
1 |
4 |
|a Cancer Research.
|
| 650 |
2 |
4 |
|a Oncology.
|
| 650 |
2 |
4 |
|a Cell Biology.
|
| 650 |
2 |
4 |
|a Molecular Medicine.
|
| 650 |
2 |
4 |
|a Biochemistry, general.
|
| 650 |
2 |
4 |
|a Biomedicine, general.
|
| 700 |
1 |
|
|a Parsyan, Armen.
|e editor.
|
| 710 |
2 |
|
|a SpringerLink (Online service)
|
| 773 |
0 |
|
|t Springer eBooks
|