Voltage Gated Sodium Channels /
| Autor Corporativo: | |
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| Otros Autores: | |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Colección: | Handbook of Experimental Pharmacology,
221 |
| Materias: |
Tabla de Contenidos:
- Overview: biophysical properties and structure of sodium channels.- The voltage sensor module in sodium channels
- Slow inactivation of Na+ channels
- Regulation/modulation of sensory neuron sodium channels
- Ubiquitylation of voltage-gated sodium channels
- Probing gating mechanisms of sodium channel using pore blockers
- Animal toxins influence voltage-gated sodium channel function
- Voltage-sensor trapping toxins: Iso form-specific ligands for sodium channels
- Pharmacological insights and quirks of bacterial sodium channels
- The role of non-pore-forming β subunits in physiology and pathophysiology of voltage-gated sodium channels
- The role of late INa in development of cardiac arrhythmias
- Proton modulation of cardiac INa: A potential arrhythmogenic trigger
- Altered sodium channel gating as molecular basis for pain: Contribution of activation, inactivation and resurgent currents. .