Validation of Alternative Methods for Toxicity Testing /
| Autor Corporativo: | |
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| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Colección: | Advances in Experimental Medicine and Biology,
856 |
| Materias: |
Tabla de Contenidos:
- Introduction
- Validation in support of internationally harmonised OECD Test Guidelines for assessing the safety of chemicals
- Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals
- Validation of alternative in vitro methods to animal testing: concepts, challenges, processes and tools
- Practical aspects of designing and conducting validation studies involving multi-study trials
- Validation of computational methods
- Implementation of New Test Methods into Practical Testing
- Pathway Based Toxicology and Fit-for-Purpose Assays
- Evidence-based toxicology
- Validation of transcriptomics-based in vitro methods
- Ensuring the quality of stem cell-derived in vitro models for toxicity testing
- Validation of bioreactor and human-on-a-chip devices for chemical safety assessment
- Integrated approaches to testing and assessment
- International harmonization and cooperation in the validation of alternative methods
- Evolving the principles and practice of validation for new alternative approaches to toxicity testing. .