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02973nam a22003975i 4500 |
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000295083 |
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20211027195659.0 |
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cr nn 008mamaa |
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100301s2009 gw | s |||| 0|eng d |
| 020 |
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|a 9783540689645
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| 024 |
7 |
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|a 10.1007/978-3-540-68964-5
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a cGMP: Generators, Effectors and Therapeutic Implications /
|c edited by Harald H. H. W. Schmidt, Franz B. Hofmann, Johannes-Peter Stasch.
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| 250 |
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|a 1st ed. 2009.
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| 260 |
# |
# |
|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 2009.
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| 300 |
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|a XIV, 583 p. 61 illus., 6 illus. in color. :
|b online resource.
|
| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Handbook of Experimental Pharmacology,
|v 191
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| 505 |
0 |
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|a Basic Generators and Effectors -- A Short History of cGMP, Guanylyl Cyclases, and cGMP-Dependent Protein Kinases -- Biochemistry of Soluble Guanylate Cyclase -- Genetic Mouse Models of the NO Receptor ‘Soluble’ Guanylyl Cyclases -- Function and Dysfunction of Mammalian Membrane Guanylyl Cyclase Receptors: Lessons from Genetic Mouse Models and Implications for Human Diseases -- Phosphodiesterases in the Central Nervous System -- Structural and Biochemical Aspects of Tandem GAF Domains -- Cyclic Nucleotide-Gated Channels -- cGMP Regulated Protein Kinases (cGK) -- cGK Substrates -- Biochemical Detection of cGMP From Past to Present: An Overview -- Novel Techniques for Real-Time Monitoring of cGMP in Living Cells -- Pharmacology of cGMP -- NO and sGC-Stimulating NO Donors -- NO-Independent, Haem-Dependent Soluble Guanylate Cyclase Stimulators -- NO- and Haem-Independent Soluble Guanylate Cyclase Activators -- Natriuretic Peptides: Their Structures, Receptors, Physiologic Functions and Therapeutic Applications -- Cyclic GMP-Hydrolyzing Phosphodiesterases -- cGMP-Dependent Protein Kinase Modulators -- cGMP-Dependent Protein Kinase as a Modifier of Behaviour -- Clinical Applications -- cGMP in the Vasculature -- Modulating cGMP to Treat Lung Diseases -- Modulation of cGMP in Heart Failure: A New Therapeutic Paradigm -- Erectile Dysfunction and Lower Urinary Tract -- cGMP and cGMP-Dependent Protein Kinase in Platelets and Blood Cells -- cGMP Signalling in the Mammalian Brain: Role in Synaptic Plasticity and Behaviour.
|
| 650 |
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0 |
|a Biochemistry.
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| 650 |
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0 |
|a Pharmacology.
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| 650 |
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0 |
|a Medical biochemistry.
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| 650 |
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0 |
|a Human physiology.
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| 650 |
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0 |
|a Molecular biology.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Pharmacology/Toxicology.
|
| 650 |
2 |
4 |
|a Medical Biochemistry.
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| 650 |
2 |
4 |
|a Human Physiology.
|
| 650 |
2 |
4 |
|a Molecular Medicine.
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| 700 |
1 |
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|a Schmidt, Harald H. H. W.
|e editor.
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| 700 |
1 |
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|a Hofmann, Franz B.
|e editor.
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| 700 |
1 |
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|a Stasch, Johannes-Peter.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|