N-Acetylaspartate A Unique Neuronal Molecule in the Central Nervous System /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Moffett, John. (Editor), Tieman, Suzannah B. (Editor), Weinberger, Daniel R. (Editor), Coyle, Joseph T. (Editor), Namboodiri, Aryan M. A. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer US : Imprint: Springer, 2006.
Edition:1st ed. 2006.
Subjects:
Online Access:https://doi.org/10.1007/0-387-30172-0
Table of Contents:
  • A Brief Overview of N-Acetylaspartate and N-Acetylaspartylglutamate
  • Expression of N-Acetylaspartate and N-Acetylaspartylglutamate in the Nervous System
  • N-Acetylaspartate Metabolism in Neural Cells
  • Naa Synthesis and Functional Roles
  • Identity of the High-Affinity Sodium/Carboxylate Cotransporter NaC3 as the N-Acetyl-L-Aspartate Transporter
  • Canavan Disease: Studies on the Knockout Mouse
  • Functions Of N-Acetylaspartate and N-Acetylaspartylglutamate in Brain
  • Control of Brain Volume during Hypoosmolality and Hyperosmolality
  • Physiological Role of N-Acetylaspartate
  • Defective Myelin Lipid Synthesis as a Pathogenic Mechanism of Canavan Disease
  • Mutation Analysis of the Aspartoacylase Gene in Non-Jewish Patients with Canavan Disease
  • Does ASPA Gene Mutation in Canavan Disease Alter Oligodendrocyte Development?
  • Quantitation of NAA in the Brain by Magnetic Resonance Spectroscopy
  • N-Acetyl-L-Aspartate in Multiple Sclerosis
  • NAA and Higher Cognitive Function in Humans
  • In Vivo NMR Measures of NAA and the Neurobiology of Schizophrenia
  • N-Acetylaspartate as a Marker of Neuronal Injury in Neurodegenerative Disease
  • Regulation of NAA-Synthesis in the Human Brain in Vivo: Canavan's Disease, Alzheimer's Disease and Schizophrenia
  • Magnetic Resonance Spectroscopy for Monitoring Neuronal Integrity in Amyotrophic Lateral Sclerosis
  • Hypoacetylaspartia: Clinical and Biochemical Follow-Up of a Patient
  • Cellular Localization of NAAG
  • Synthesis of N-Acetylaspartylglutamate (NAAG) and N-Acetylaspartate (NAA) in Axons and Glia of the Crayfish Medial Giant Nerve Fiber
  • NAAG as a Neurotransmitter
  • Glutamate Carboxypeptidase II (NAALADase) Inhibition as a Novel Therapeutic Strategy
  • N-Acetylaspartylglutamate (NAAG) in Spinal Cord Injury and Disease
  • N-Acetylaspartylglutamate (NAAG) in Pelizaeusmerzbacher Disease
  • Concluding Remarks.