The Kinetochore: From Molecular Discoveries to Cancer Therapy /

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: De Wulf, Peter. (Editor), Earnshaw, William. (Editor)
Format: eBook
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2009.
Edition:1st ed. 2009.
Subjects:
Online Access:https://doi.org/10.1007/978-0-387-69076-6
Table of Contents:
  • Centromeres and Kinetochores: An Historical Perspective
  • The Basics of Chromosome Segregation
  • The Centromere
  • Neocentromeres
  • Human Artificial Centromeres: Assembly of Functional Centromeres on Human Artificial Chromosomes
  • Kinetochore Composition, Formation, and Organization
  • Evolution of Centromeres and Kinetochores: A Two-Part Fugue
  • Mitotic Spindle Assembly Mechanisms
  • Kinetochore-Microtubule Interactions
  • Post-Translational Modifications that Regulate Kinetochore Activity
  • The Role of the Kinetochore in Spindle Checkpoint Signaling
  • Kinetochore Regulation of Anaphase and Cytokinesis
  • Roles of Centromeres and Kinetochores in Meiosis
  • The Kinetochore-Cancer Connection
  • The Kinetochore as Target for Cancer Drug Development.