Lipoxygenases and their Metabolites Biological Functions /
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , |
| Formato: | eBook |
| Lenguaje: | English |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
1999.
|
| Edición: | 1st ed. 1999. |
| Colección: | Advances in Experimental Medicine and Biology,
447 |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1007/978-1-4615-4861-4 |
Tabla de Contenidos:
- 1. Introductory Remarks: Historical Roots and Contemporary Aspects of Lipoxygenase Research
- I: Enzymology, Molecular Biology, and Biological Functions of Mammalian Lipoxygenases
- 2. Mammalian 15-Lipoxygenases: Enzymatic Properties and Biological Implications
- 3. Molecular Cloning of a Second Human 15S-Lipoxygenase and Its Murine Homologue, an 8S-Lipoxygenase: Their Relationship to Other Mammalian Lipoxygenases
- 4. Arachidonate 12-Lipoxygenase Isozymes
- 5. Expression of Leukocyte-Type 12-Lipoxygenase and Reticulocyte-Type 15-Lipoxygenase in Rabbits
- 6. Lipoxygenase Gene Disruption Studies: Status and Applications
- II: Metabolic Regulation of Lipoxygenases: Lipoxygenase Inhibitors
- 7. The Release of Polyunsaturated Fatty Acids and Their Lipoxygenation in the Brain
- 8. Biological Relevance of the 12-Lipoxygenase Pathway for Platelet and Lymphocyte Functions
- 9. Effect of 15-HETE on the 5-Lipoxygenase Pathway in Neutrophils: Genuine Inhibitor or Alternative Substrate?
- 10. Adenosine: An Endogenous Inhibitor of Arachidonic Acid Release and Leukotriene Biosynthesis in Human Neutrophils
- 11. Pharmacological Aspects of 5-Lipoxygenase Inhibition
- III: Products of the Lipoxygenase Pathways and Their Receptors
- 12. The Hepoxilins: A Review
- 13. Aspirin-Triggered 15-Epi-Lipoxin A4 and Stable Analogs of Lipoxin A4 Are Potent Inhibitors of Acute Inflammation: Receptors and Pathways
- 14. Modulation of LTB4 Receptor in T-Lymphocytes by Lipoxin A4 (LXA4) and Its Role in Delayed-Type Hypersensitivity
- 15. Receptors for Cysteinyl-Leukotrienes in Human Cells
- 16. Cysteinyl-Leukotrienes and the Human Lung
- 17. 12(S)-HETE in Cancer Metastasis
- 18. A 12(S)-EETE Receptor in Lewis Lung Carcinoma Cells
- 19. Fatty Acids, Eicosanoids, and Hypolipidemic Agents Regulate Gene Expression through Direct Binding to Peroxisome Proliferator-Activated Receptors
- 20. Biogenesis and Biological Function of Marine Algal Oxylipins
- Contributors.