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02124nam a22002895i 4500 |
| 001 |
978-1-59259-290-6 |
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20190618101635.0 |
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cr nn 008mamaa |
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100301s2002 xxu| s |||| 0|eng d |
| 020 |
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|a 9781592592906
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| 024 |
7 |
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|a 10.1385/1592592902
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Peptide Nucleic Acids
|b Methods and Protocols /
|c edited by Peter E. Nielsen.
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| 250 |
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|a 1st ed. 2002.
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| 260 |
# |
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|a Totowa, NJ :
|b Humana Press :
|b Imprint: Humana,
|c 2002.
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| 300 |
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|a X, 274 p.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 208
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| 505 |
0 |
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|a PNA Technology -- Chemistry -- Solid Phase Synthesis of PNA Oligomers -- Synthesis of PNA-Peptide Conjugates -- Parallel Synthesis of PNA-Peptide Conjugate Libraries -- Thermodynamics of PNA Interactions with DNA and RNA -- PNA Technology -- Measurement of PNA Binding to Double-Stranded DNA -- PNA-Mediated Immobilization of Supercoiled DNA -- PNA Openers and Their Applications -- Colorimetric Detection of PNA-DNA Hybridization Using Cyanine Dyes -- Diagnostics -- PNA-Mediated PCR Clamping -- PNA Clamping Techniques for the Determination of Oncogene Mutations -- PNA Fluorescent In Situ Hybridization for Rapid Microbiology and Cytogenetic Analysis -- Detection of Point Mutations Using PNA-Containing Electrophoresis Matrices -- Antisense and Antigene -- Lipid-Mediated Introduction of Peptide Nucleic Acids Into Cells -- Synthesis of Cell-Penetrating Peptide-PNA Constructs -- Antisense Inhibition of Bacterial Gene Expression and Cell Growth -- In Vitro Transcription from Peptide Nucleic Acid/DNA Strand Displacement Loops -- Animal Studies -- In Vitro and In Vivo Studies on the Pharmacokinetics and Metabolism of PNA Constructs in Rodents.
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| 650 |
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|a Biochemistry.
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| 650 |
1 |
4 |
|a Biochemistry, general.
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| 700 |
1 |
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|a Nielsen, Peter E.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 856 |
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|u https://doi.org/10.1385/1592592902
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