Peptide Nucleic Acids Methods and Protocols /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Nielsen, Peter E. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2002.
Edición:1st ed. 2002.
Colección:Methods in Molecular Biology, 208
Materias:
Acceso en línea:https://doi.org/10.1385/1592592902
Tabla de Contenidos:
  • PNA Technology
  • Chemistry
  • Solid Phase Synthesis of PNA Oligomers
  • Synthesis of PNA-Peptide Conjugates
  • Parallel Synthesis of PNA-Peptide Conjugate Libraries
  • Thermodynamics of PNA Interactions with DNA and RNA
  • PNA Technology
  • Measurement of PNA Binding to Double-Stranded DNA
  • PNA-Mediated Immobilization of Supercoiled DNA
  • PNA Openers and Their Applications
  • Colorimetric Detection of PNA-DNA Hybridization Using Cyanine Dyes
  • Diagnostics
  • PNA-Mediated PCR Clamping
  • PNA Clamping Techniques for the Determination of Oncogene Mutations
  • PNA Fluorescent In Situ Hybridization for Rapid Microbiology and Cytogenetic Analysis
  • Detection of Point Mutations Using PNA-Containing Electrophoresis Matrices
  • Antisense and Antigene
  • Lipid-Mediated Introduction of Peptide Nucleic Acids Into Cells
  • Synthesis of Cell-Penetrating Peptide-PNA Constructs
  • Antisense Inhibition of Bacterial Gene Expression and Cell Growth
  • In Vitro Transcription from Peptide Nucleic Acid/DNA Strand Displacement Loops
  • Animal Studies
  • In Vitro and In Vivo Studies on the Pharmacokinetics and Metabolism of PNA Constructs in Rodents.