Tumor Suppressor Genes Volume 2: Regulation, Function, and Medicinal Applications /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: El-Deiry, Wafik S. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2003.
Edición:1st ed. 2003.
Colección:Methods in Molecular Biology, 223
Materias:
Acceso en línea:https://doi.org/10.1385/1592593291
Tabla de Contenidos:
  • Understanding the Function and Regulation of Tumor Suppressor Genes
  • Utilizing NMR to Study the Structure of Growth-Inhibitory Proteins
  • Generation and Application of Phospho-specific Antibodies for p53 and pRB
  • Stability and Ubiquitination of the Tumor Suppressor Protein p53
  • Role of Tumor Suppressors in DNA Damage Response
  • In Situ Hybridization in Cancer and Normal Tissue
  • Genetic Strategies in Saccharomyces cerevisiae to Study Human Tumor Suppressor Genes
  • Electrophoretic Mobility Shift Analysis of the DNA Binding of Tumor Suppressor Gene Products
  • Analysis of Gene Promoter Regulation by Tumor Suppressor Genes
  • DNA Footprinting
  • Identification of DNA-Binding of Tumor Suppressor Genes by Chromatin Immunoprecipitation
  • Co-immunoprecipitation of Tumor Suppressor Protein-Interacting Proteins
  • Microarray Approaches for Analysis of Tumor Suppressor Gene Function
  • Analysis of Tumor Suppressor Gene-Induced Senescence
  • Yeast Two-Hybrid Screening as a Means of Deciphering Tumor Suppressor Pathways
  • Somatic Cell Knockouts of Tumor Suppressor Genes
  • Colony Growth Suppression by Tumor Suppressor Genes
  • Flow Cytometric Analysis of Cell Cycle Control by Tumor Suppressor Genes
  • Analysis of Cyclin-Dependent Kinase Activity
  • Tumor Suppressor Gene-Inducible Cell Lines
  • In Vitro Models of Early Neoplastic Transformation of Human Mammary Epithelial Cells
  • Tumor Suppression Through Angiogenesis Inhibition
  • Flow Cytometric Analysis of Tumor Suppressor Gene-Induced Apoptosis
  • Functional Analysis of Tumor Suppressor Genes in Mice
  • The Tissue Microenvironment as an Epigenetic Tumor Modifier
  • Analyzing the Function of Tumor Suppressor Genes Using a Drosophila Model
  • Assembling a Tumor Progression Model
  • Conformation-Sensitive Gel Electrophoresis for Detecting BRCA1 Mutations
  • Medicinal Applications of Tumor Suppessors
  • Conversion Technology and Cancer Predispositions
  • Discovering Novel Anticancer Drugs
  • Targets in Apoptosis Signaling
  • Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function
  • Hormonal and Differentiation Agents in Cancer Growth Suppression
  • Regulation of NF-?B by Oncoproteins and Tumor Suppressor Proteins
  • Blocking Survivin to Kill Cancer Cells
  • Targeting the Mitochondria to Enhance Tumor Suppression
  • Novel Approaches to Screen for Anticancer Drugs Using Saccharomyces cerevisiae
  • Tumor Suppressor Gene Therapy
  • Therapeutic Strategies Using Inhibitors of Angiogenesis
  • Isolation of p53 Inhibitors by Screening Chemical Libraries in Cell-Based Readout System.